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Ccdc117 Gene Detail
Summary
  • Symbol
    Ccdc117
  • Name
    coiled-coil domain containing 117
  • Synonyms
    1110004K02Rik, 1700026O03Rik, MGC:30640
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144383
    NCBI Gene: 104479
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:5478887-5492187 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 3.61 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144383
 protein coding gene Chr11:5478887-5492217 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018002
 protein coding gene Chr11:2592205-2606779 (-)
A/J MGP_AJ_G0017975
 protein coding gene Chr11:2497869-2510870 (-)
AKR/J MGP_AKRJ_G0017939
 protein coding gene Chr11:2631685-2644949 (-)
BALB/cJ MGP_BALBcJ_G0017943
 protein coding gene Chr11:2487683-2501101 (-)
C3H/HeJ MGP_C3HHeJ_G0017756
 protein coding gene Chr11:2503929-2516847 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018395
 protein coding gene Chr11:2660798-2675908 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016053
 protein coding gene Chr11:2389167-2401660 (-)
CAST/EiJ MGP_CASTEiJ_G0017318
 protein coding gene Chr11:2464845-2479105 (-)
CBA/J MGP_CBAJ_G0017731
 protein coding gene Chr11:2985735-3001911 (-)
DBA/2J MGP_DBA2J_G0017841
 protein coding gene Chr11:2396457-2409575 (-)
FVB/NJ MGP_FVBNJ_G0017833
 protein coding gene Chr11:2437797-2450566 (-)
LP/J MGP_LPJ_G0017912
 protein coding gene Chr11:2666422-2681380 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017859
 protein coding gene Chr11:2615963-2634443 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018435
 protein coding gene Chr11:2614568-2629653 (-)
PWK/PhJ MGP_PWKPhJ_G0017098
 protein coding gene Chr11:2424295-2438594 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016895
 protein coding gene Chr11:2604909-2617406 (-)
WSB/EiJ MGP_WSBEiJ_G0017372
 protein coding gene Chr11:2475007-2491274 (-)



Homology
more
  • Human Ortholog
    CCDC117, coiled-coil domain containing 117
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC117, coiled-coil domain containing 117
  • Synonyms
    dJ366L4.1
  • Links
    NCBI Gene ID: 150275
    neXtProt AC: NX_Q8IWD4
    UniProt: Q8IWD4

  • Chr Location
    22q12.1; chr22:28772674-28789301 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    18
  • cDNA Data
    123
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020482 Ensembl Gene Model | MGI Sequence Detail 13301 C57BL/6J ±  kb
    transcript ENSMUST00000020776 Ensembl | MGI Sequence Detail 3372 Not Applicable  
    polypeptide ENSMUSP00000020776 Ensembl | MGI Sequence Detail 277 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 124
      cDNA 123
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1914941, MGI:1915705, MGI:2144434, MGI:2144462
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 5
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:276152 Horton AJ, et al., Nkx2-5 Second Heart Field Target Gene Ccdc117 Regulates DNA Metabolism and Proliferation. Sci Rep. 2019 Feb 11;9(1):1738
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory