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Iffo2 Gene Detail
Summary
  • Symbol
    Iffo2
  • Name
    intermediate filament family orphan 2
  • Synonyms
    MGC:36549
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140675
    NCBI Gene: 212632
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:139257859-139347693 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 70.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1055 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140675
protein coding gene Chr4:139257859-139347693 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029019
protein coding gene Chr4:142416391-142466826 (+)
A/J MGP_AJ_G0028978
protein coding gene Chr4:136295573-136342827 (+)
AKR/J MGP_AKRJ_G0028930
protein coding gene Chr4:140200834-140246832 (+)
BALB/cJ MGP_BALBcJ_G0029002
protein coding gene Chr4:136973642-137019674 (+)
C3H/HeJ MGP_C3HHeJ_G0028716
protein coding gene Chr4:140592141-140639197 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029443
protein coding gene Chr4:147463956-147519954 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026714
protein coding gene Chr4:129247161-129293562 (+)
CAST/EiJ MGP_CASTEiJ_G0028148
protein coding gene Chr4:138782775-138831172 (+)
CBA/J MGP_CBAJ_G0028680
protein coding gene Chr4:151708181-151762600 (+)
DBA/2J MGP_DBA2J_G0028830
protein coding gene Chr4:136695879-136742863 (+)
FVB/NJ MGP_FVBNJ_G0028797
protein coding gene Chr4:135732912-135778712 (+)
LP/J MGP_LPJ_G0028929
protein coding gene Chr4:142503021-142545248 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028823
protein coding gene Chr4:155604982-155654085 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029481
protein coding gene Chr4:140725788-140772779 (+)
PWK/PhJ MGP_PWKPhJ_G0027869
protein coding gene Chr4:133542377-133591033 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027694
protein coding gene Chr4:136518833-136567675 (+)
WSB/EiJ MGP_WSBEiJ_G0028226
protein coding gene Chr4:140987583-141039894 (+)



Homology
more
  • Human Ortholog
    IFFO2, intermediate filament family orphan 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFFO2, intermediate filament family orphan 2
  • Links
    NCBI Gene ID: 126917
    neXtProt AC: NX_Q5TF58
    UniProt: Q5TF58

  • Chr Location
    1p36.13; chr1:18904280-18956676 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 212632 NCBI Gene Model | MGI Sequence Detail 89835 C57BL/6J ±  kb
transcript NM_001205173 RefSeq | MGI Sequence Detail 5763 C57BL/6  
polypeptide Q8R2V2 UniProt | EBI | MGI Sequence Detail 512 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 5
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory