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Clca4a Gene Detail
Summary
  • Symbol
    Clca4a
  • Name
    chloride channel accessory 4A
  • Synonyms
    9130020L07Rik, Clca6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139744
    NCBI Gene: 99663
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:144658247-144680806 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 69.22 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139744
 protein coding gene Chr3:144658241-144680806 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0027913
 protein coding gene Chr3:142969869-143082405 (-)
AKR/J MGP_AKRJ_G0027879
 protein coding gene Chr3:146742181-146879736 (-)
BALB/cJ MGP_BALBcJ_G0027925
 protein coding gene Chr3:142760697-142896905 (-)
C3H/HeJ MGP_C3HHeJ_G0027655
 protein coding gene Chr3:147119466-147246599 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028369
 protein coding gene Chr3:153425632-153460647 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025708
 protein coding gene Chr3:138032539-138057126 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0027738
 protein coding gene Chr3:139625988-139651237 (-)
LP/J MGP_LPJ_G0027882
 protein coding gene Chr3:149685041-149706699 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027771
 protein coding gene Chr3:167082935-167108563 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028428
 protein coding gene Chr3:146446580-146472320 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CLCA4, chloride channel accessory 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLCA4, chloride channel accessory 4
  • Synonyms
    CaCC, CaCC2
  • Links
    NCBI Gene ID: 22802
    neXtProt AC: NX_Q14CN2
    UniProt: Q14CN2

  • Chr Location
    1p22.3; chr1:86547078-86580754 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    8
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 99663 NCBI Gene Model | MGI Sequence Detail 22560 C57BL/6J ±  kb
transcript NM_207208 RefSeq | MGI Sequence Detail 2998 C57BL/6  
polypeptide Q6Q473 UniProt | EBI | MGI Sequence Detail 924 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 6
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory