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Igsf9 Gene Detail
Summary
  • Symbol
    Igsf9
  • Name
    immunoglobulin superfamily, member 9
  • Synonyms
    Dasm1, mKIAA1355, NRT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135283
    NCBI Gene: 93842
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:172309355-172326445 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 79.86 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    183 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135283
 protein coding gene Chr1:172307616-172326445 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016789
 protein coding gene Chr1:178351029-178368082 (+)
A/J MGP_AJ_G0016768
 protein coding gene Chr1:171060057-171079026 (+)
AKR/J MGP_AKRJ_G0016734
 protein coding gene Chr1:176223254-176240309 (+)
BALB/cJ MGP_BALBcJ_G0016729
 protein coding gene Chr1:171598165-171615234 (+)
C3H/HeJ MGP_C3HHeJ_G0016553
 protein coding gene Chr1:176797201-176814260 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017191
 protein coding gene Chr1:184277152-184294238 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014897
 protein coding gene Chr1:162752787-162769811 (+)
CAST/EiJ MGP_CASTEiJ_G0016133
 protein coding gene Chr1:176165966-176183057 (+)
CBA/J MGP_CBAJ_G0016527
 protein coding gene Chr1:190822930-190840096 (+)
DBA/2J MGP_DBA2J_G0016634
 protein coding gene Chr1:169985618-170002744 (+)
FVB/NJ MGP_FVBNJ_G0016631
 protein coding gene Chr1:168241504-168259549 (+)
LP/J MGP_LPJ_G0016705
 protein coding gene Chr1:179435813-179452887 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016658
 protein coding gene Chr1:198056818-198073871 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017227
 protein coding gene Chr1:176092935-176111033 (+)
PWK/PhJ MGP_PWKPhJ_G0015919
 protein coding gene Chr1:169367045-169384213 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015701
 protein coding gene Chr1:175050097-175067189 (+)
WSB/EiJ MGP_WSBEiJ_G0016195
 protein coding gene Chr1:176244144-176262816 (+)



Homology
more
  • Human Ortholog
    IGSF9, immunoglobulin superfamily member 9
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGSF9, immunoglobulin superfamily member 9
  • Synonyms
    FP18798, IGSF9A, Nrt1
  • Links
    NCBI Gene ID: 57549
    neXtProt AC: NX_Q9P2J2
    UniProt: Q9P2J2

  • Chr Location
    1q23.2; chr1:159927039-159945613 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 3 alleles in 3 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation are viable and fertile but show abnormal miniature inhibitory postsynaptic currents and increased susceptibility to pharmacologically induced seizures.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    921
  • Tissues
    68
  • cDNA Data
    105
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037995 Ensembl Gene Model | MGI Sequence Detail 17091 C57BL/6J ±  kb
    transcript ENSMUST00000052629 Ensembl | MGI Sequence Detail 4133 Not Applicable  
    polypeptide ENSMUSP00000058275 Ensembl | MGI Sequence Detail 1179 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 112
      Genomic 1
      cDNA 106
      Primer pair 3
      Other 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2135331
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 8
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:68343 Doudney K, et al., Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. Genomics. 2001 Mar 1;72(2):180-92
    • Latest
      J:306704 Wang XX, et al., MRCKbeta links Dasm1 to actin rearrangements to promote dendrite development. J Biol Chem. 2021 Apr 29;:100730
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory