Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tcf15tm1Eno
Name:	transcription factor 15; targeted mutation 1, Eric N Olson
MGI ID:	MGI:1929775
Synonyms:	paraxis-, paraxis-null
Gene:	Tcf15  Location: Chr2:151985481-151991017 bp, + strand  Genetic Position: Chr2, 74.83 cM
Alliance:	Tcf15tm1Eno page

Germline Transmission:	Earliest citation of germline transmission: J:37117
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Replacement of sequences from the initiating codon through the basic helix-loop-helix (bHLH) region through part of the first intron with a PGK-neomycin cassette. No functional mRNA was detected in homozygous mutants by Northern blot analysis. (J:37117)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	139 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	21 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf15 Mutation:	11 strains or lines available

Original:	J:37117 Burgess R, et al., Requirement of the paraxis gene for somite formation and musculoskeletal patterning. Nature. 1996 Dec 12;384(6609):570-3
All:	9 reference(s)