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Fam151b Gene Detail
Summary
  • Symbol
    Fam151b
  • Name
    family with sequence similarity 151, member B
  • Synonyms
    4930405M20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921192
    NCBI Gene: 73942
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:92586133-92620523 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 47.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    318 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921192
protein coding gene Chr13:92586128-92620539 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020816
protein coding gene Chr13:93752304-93787770 (-)
A/J MGP_AJ_G0020770
protein coding gene Chr13:90289096-90327069 (-)
AKR/J MGP_AKRJ_G0020743
protein coding gene Chr13:93017508-93052726 (-)
BALB/cJ MGP_BALBcJ_G0020766
protein coding gene Chr13:90927109-90961576 (-)
C3H/HeJ MGP_C3HHeJ_G0020560
protein coding gene Chr13:92728095-92765878 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021203
protein coding gene Chr13:96607161-96642530 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018770
protein coding gene Chr13:86208541-86242454 (-)
CAST/EiJ MGP_CASTEiJ_G0020079
protein coding gene Chr13:91989813-92022258 (-)
CBA/J MGP_CBAJ_G0020519
protein coding gene Chr13:100448702-100491496 (-)
DBA/2J MGP_DBA2J_G0020644
protein coding gene Chr13:90041401-90074844 (-)
FVB/NJ MGP_FVBNJ_G0020624
protein coding gene Chr13:88865505-88899918 (-)
LP/J MGP_LPJ_G0020717
protein coding gene Chr13:93874222-93910148 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020653
protein coding gene Chr13:100947688-100982370 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021243
protein coding gene Chr13:92424571-92460338 (-)
PWK/PhJ MGP_PWKPhJ_G0019831
protein coding gene Chr13:88793524-88827219 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019655
protein coding gene Chr13:88684150-88718743 (-)
WSB/EiJ MGP_WSBEiJ_G0020136
protein coding gene Chr13:92904653-92940278 (-)



Homology
more
  • Human Ortholog
    FAM151B, family with sequence similarity 151 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM151B, family with sequence similarity 151 member B
  • Synonyms
    UNQ9217
  • Links
    NCBI Gene ID: 167555
    neXtProt AC: NX_Q6UXP7
    UniProt: Q6UXP7

  • Chr Location
    5q14.1; chr5:80487969-80542563 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout results in photoreceptor outer segment degeneration shortly after eye opening.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034334 Ensembl Gene Model | MGI Sequence Detail 34391 C57BL/6J ±  kb
    transcript ENSMUST00000040106 Ensembl | MGI Sequence Detail 1152 Not Applicable  
    polypeptide ENSMUSP00000045024 Ensembl | MGI Sequence Detail 279 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 3
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:284934 Findlay AS, et al., Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. Sci Rep. 2020 Jan 16;10(1):437

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory