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Dip2c Gene Detail
Summary
  • Symbol
    Dip2c
  • Name
    disco interacting protein 2 homolog C
  • Synonyms
    2900024P20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920179
    NCBI Gene: 208440
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:9326564-9718964 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 3.70 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3460 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920179
 protein coding gene Chr13:9326530-9718964 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020224
 protein coding gene Chr13:5929481-6327021 (+)
A/J MGP_AJ_G0020180
 protein coding gene Chr13:5901345-6302289 (+)
AKR/J MGP_AKRJ_G0020155
 protein coding gene Chr13:5975048-6383058 (+)
BALB/cJ MGP_BALBcJ_G0020163
 protein coding gene Chr13:5902417-6290542 (+)
C3H/HeJ MGP_C3HHeJ_G0019967
 protein coding gene Chr13:6097230-6511917 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020610
 protein coding gene Chr13:6273650-6691026 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018217
 protein coding gene Chr13:5845824-6231590 (+)
CAST/EiJ MGP_CASTEiJ_G0019505
 protein coding gene Chr13:5818662-6210430 (+)
CBA/J MGP_CBAJ_G0019934
 protein coding gene Chr13:6415264-6838247 (+)
DBA/2J MGP_DBA2J_G0020051
 protein coding gene Chr13:5749037-6142010 (+)
FVB/NJ MGP_FVBNJ_G0020036
 protein coding gene Chr13:5589541-5972662 (+)
LP/J MGP_LPJ_G0020125
 protein coding gene Chr13:6015797-6424283 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020072
 protein coding gene Chr13:6745003-7148617 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020638
 protein coding gene Chr13:5932000-6326433 (+)
PWK/PhJ MGP_PWKPhJ_G0019268
 protein coding gene Chr13:5818106-6199083 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019075
 protein coding gene Chr13:5916737-6300059 (+)
WSB/EiJ MGP_WSBEiJ_G0019565
 protein coding gene Chr13:5843366-6250583 (+)



Homology
more
  • Human Ortholog
    DIP2C, disco interacting protein 2 homolog C
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DIP2C, disco interacting protein 2 homolog C
  • Synonyms
    KIAA0934
  • Links
    NCBI Gene ID: 22982
    neXtProt AC: NX_Q9Y2E4
    UniProt: Q9Y2E4

  • Chr Location
    10p15.3; chr10:274201-689668 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 3 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit premature lethality. Mice homozygous for a hypomorph exhibit female infertility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    61
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000048264 Ensembl Gene Model | MGI Sequence Detail 392401 C57BL/6J ±  kb
    transcript ENSMUST00000166299 Ensembl | MGI Sequence Detail 4822 Not Applicable  
    polypeptide ENSMUSP00000126827 Ensembl | MGI Sequence Detail 1557 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      10 Sequences
    • InterPro Domains
      IPR045851 AMP-binding enzyme, C-terminal domain superfamily
      IPR000873 AMP-dependent synthetase/ligase domain
      IPR042099 ANL, N-terminal domain
      IPR037337 Dip2-like domain
      IPR010506 DMAP1-binding domain
    Molecular
    Reagents
    less
    • All nucleic 61
      cDNA 61

      Microarray probesets 7
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:339899 Oo ZM, et al., Brain transcriptome study through CRISPR/Cas9 mediated mouse Dip2c gene knock-out. Gene. 2020 Oct 20;758:144975
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory