About   Help   FAQ
Elf2 Gene Detail
Summary
  • Symbol
    Elf2
  • Name
    E74-like factor 2
  • Synonyms
    2610036A20Rik, A230104O07Rik, NERF-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916507
    NCBI Gene: 69257
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:51160141-51248084 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 22.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    599 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916507
protein coding gene Chr3:51160141-51248101 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027194
protein coding gene Chr3:49715708-49803173 (-)
A/J MGP_AJ_G0027154
protein coding gene Chr3:48261239-48351780 (-)
AKR/J MGP_AKRJ_G0027123
protein coding gene Chr3:49216850-49307218 (-)
BALB/cJ MGP_BALBcJ_G0027166
protein coding gene Chr3:48116447-48206743 (-)
C3H/HeJ MGP_C3HHeJ_G0026909
protein coding gene Chr3:49432864-49529080 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027612
protein coding gene Chr3:51705188-51807252 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024972
protein coding gene Chr3:44901511-44988085 (-)
CAST/EiJ MGP_CASTEiJ_G0026362
protein coding gene Chr3:49491807-49586802 (-)
CBA/J MGP_CBAJ_G0026886
protein coding gene Chr3:53321026-53420596 (-)
DBA/2J MGP_DBA2J_G0027020
protein coding gene Chr3:47873213-47964970 (-)
FVB/NJ MGP_FVBNJ_G0026988
protein coding gene Chr3:46851535-46940074 (-)
LP/J MGP_LPJ_G0027132
protein coding gene Chr3:50464859-50555468 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027006
protein coding gene Chr3:57524770-57616849 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027671
protein coding gene Chr3:49143840-49235356 (-)
PWK/PhJ MGP_PWKPhJ_G0026094
protein coding gene Chr3:47505529-47596396 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025907
protein coding gene Chr3:48787054-48877526 (-)
WSB/EiJ MGP_WSBEiJ_G0026436
protein coding gene Chr3:49242049-49338231 (-)



Homology
more
  • Human Ortholog
    ELF2, E74 like ETS transcription factor 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ELF2, E74 like ETS transcription factor 2
  • Synonyms
    EU32, NERF, NERF-1A, NERF-1a,b, NERF-1B, NERF-2
  • Links
    NCBI Gene ID: 1998
    neXtProt AC: NX_Q15723
    UniProt: Q15723

  • Chr Location
    4q31.1; chr4:139028112-139177915 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037174 Ensembl Gene Model | MGI Sequence Detail 87944 C57BL/6J ±  kb
transcript ENSMUST00000163748 Ensembl | MGI Sequence Detail 2656 Not Applicable  
polypeptide ENSMUSP00000126871 Ensembl | MGI Sequence Detail 593 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 21
    Primer pair 3
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139969, MGI:2140032
References
more
  • Summaries
    All 59
    Developmental Gene Expression 16
    Diseases 1
    Gene Ontology 6
    Phenotypes 16
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:321553 Neupane S, et al., O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development. Matrix Biol. 2022 Feb 12;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory