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Diras2 Gene Detail
Summary
  • Symbol
    Diras2
  • Name
    DIRAS family, GTP-binding RAS-like 2
  • Synonyms
    2900052J15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915453
    NCBI Gene: 68203
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:52658416-52685315 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 27.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    93 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915453
 protein coding gene Chr13:52658411-52685390 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020556
 protein coding gene Chr13:51778622-51807627 (-)
A/J MGP_AJ_G0020510
 protein coding gene Chr13:49929084-49955544 (-)
AKR/J MGP_AKRJ_G0020488
 protein coding gene Chr13:51351475-51379106 (-)
BALB/cJ MGP_BALBcJ_G0020506
 protein coding gene Chr13:50126388-50152847 (-)
C3H/HeJ MGP_C3HHeJ_G0020305
 protein coding gene Chr13:51186458-51214674 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020940
 protein coding gene Chr13:53379865-53407501 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018522
 protein coding gene Chr13:47709113-47736650 (-)
CAST/EiJ MGP_CASTEiJ_G0019819
 protein coding gene Chr13:51178717-51211336 (-)
CBA/J MGP_CBAJ_G0020265
 protein coding gene Chr13:55390981-55418224 (-)
DBA/2J MGP_DBA2J_G0020388
 protein coding gene Chr13:49492793-49519164 (-)
FVB/NJ MGP_FVBNJ_G0020367
 protein coding gene Chr13:48932850-48960846 (-)
LP/J MGP_LPJ_G0020464
 protein coding gene Chr13:52056499-52083859 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020396
 protein coding gene Chr13:54989070-55018169 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020983
 protein coding gene Chr13:50941920-50969393 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0019881
 protein coding gene Chr13:51267348-51294930 (-)



Homology
more
  • Human Ortholog
    DIRAS2, DIRAS family GTPase 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DIRAS2, DIRAS family GTPase 2
  • Synonyms
    Di-Ras2
  • Links
    NCBI Gene ID: 54769
    neXtProt AC: NX_Q96HU8
    UniProt: Q96HU8

  • Chr Location
    9q22.2; chr9:90609832-90642862 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Targeted
    2
  • Genomic Mutations
    1 involving Diras2
  • Find Mice (IMSR)
    20 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    13
  • cDNA Data
    57
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047842 Ensembl Gene Model | MGI Sequence Detail 26900 C57BL/6J ±  kb
transcript ENSMUST00000057442 Ensembl | MGI Sequence Detail 4786 Not Applicable  
polypeptide ENSMUSP00000055416 Ensembl | MGI Sequence Detail 199 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 59
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145227
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:310851 Grunewald L, et al., Expression of the ADHD candidate gene Diras2 in the brain. J Neural Transm (Vienna). 2018 Jun;125(6):913-923
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory