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Rnf115 Gene Detail
Summary
  • Symbol
    Rnf115
  • Name
    ring finger protein 115
  • Synonyms
    2610028E05Rik, Rabring7, Zfp364
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915095
    NCBI Gene: 67845
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96634869-96698471 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 41.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915095
 protein coding gene Chr3:96634869-96698954 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027632
 protein coding gene Chr3:97620591-97693668 (+)
A/J MGP_AJ_G0027594
 protein coding gene Chr3:94498879-94564842 (+)
AKR/J MGP_AKRJ_G0027561
 protein coding gene Chr3:96733300-96808273 (+)
BALB/cJ MGP_BALBcJ_G0027604
 protein coding gene Chr3:94308453-94377628 (+)
C3H/HeJ MGP_C3HHeJ_G0027336
 protein coding gene Chr3:97033334-97097499 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028050
 protein coding gene Chr3:101179402-101255194 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025391
 protein coding gene Chr3:90772744-90841408 (+)
CAST/EiJ MGP_CASTEiJ_G0026791
 protein coding gene Chr3:96289886-96364163 (+)
CBA/J MGP_CBAJ_G0027311
 protein coding gene Chr3:104887537-104965878 (+)
DBA/2J MGP_DBA2J_G0027454
 protein coding gene Chr3:93826887-93892091 (+)
FVB/NJ MGP_FVBNJ_G0027423
 protein coding gene Chr3:91837416-91903576 (+)
LP/J MGP_LPJ_G0027559
 protein coding gene Chr3:98902684-98972199 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027449
 protein coding gene Chr3:110970638-111044469 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028104
 protein coding gene Chr3:96342993-96413109 (+)
PWK/PhJ MGP_PWKPhJ_G0026516
 protein coding gene Chr3:93661526-93728910 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026338
 protein coding gene Chr3:94640482-94713688 (+)
WSB/EiJ MGP_WSBEiJ_G0026869
 protein coding gene Chr3:96793134-96863324 (+)



Homology
more
  • Human Ortholog
    RNF115, ring finger protein 115
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF115, ring finger protein 115
  • Synonyms
    BCA2, RABRING7, ZFP364, ZNF364
  • Links
    NCBI Gene ID: 27246
    neXtProt AC: NX_Q9Y4L5
    UniProt: Q9Y4L5

  • Chr Location
    1q21.1; chr1:145738868-145824095 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit hypo- and hyper-sensitivity to EMCV and HSV-1 infection, respectively.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    778
  • Tissues
    48
  • cDNA Data
    82
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67845 NCBI Gene Model | MGI Sequence Detail 63603 C57BL/6J ±  kb
    transcript NM_026406 RefSeq | MGI Sequence Detail 2265 Not Specified  
    polypeptide Q9D0C1 UniProt | EBI | MGI Sequence Detail 305 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 82
      cDNA 82

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2139912
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 9
      Phenotypes 14
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory