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Fam120b Gene Detail
Summary
  • Symbol
    Fam120b
  • Name
    family with sequence similarity 120, member B
  • Synonyms
    4932442K08Rik, CCPG
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914794
    NCBI Gene: 67544
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:15616464-15653843 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 8.95 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    296 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914794
 protein coding gene Chr17:15616464-15653845 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023173
 protein coding gene Chr17:13232582-13270728 (+)
A/J MGP_AJ_G0023139
 protein coding gene Chr17:12987487-13024698 (+)
AKR/J MGP_AKRJ_G0023109
 protein coding gene Chr17:12950891-12988129 (+)
BALB/cJ MGP_BALBcJ_G0023139
 protein coding gene Chr17:12936741-12974088 (+)
C3H/HeJ MGP_C3HHeJ_G0022900
 protein coding gene Chr17:13137480-13175828 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023582
 protein coding gene Chr17:13846234-13883987 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021094
 protein coding gene Chr17:11001869-11041715 (+)
CAST/EiJ MGP_CASTEiJ_G0022417
 protein coding gene Chr17:13051003-13089068 (+)
CBA/J MGP_CBAJ_G0022876
 protein coding gene Chr17:14294597-14332856 (+)
DBA/2J MGP_DBA2J_G0023009
 protein coding gene Chr17:12709061-12746269 (+)
FVB/NJ MGP_FVBNJ_G0022975
 protein coding gene Chr17:12553842-12591519 (+)
LP/J MGP_LPJ_G0023083
 protein coding gene Chr17:13224695-13261940 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022998
 protein coding gene Chr17:13831474-13869325 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023618
 protein coding gene Chr17:13187155-13225739 (+)
PWK/PhJ MGP_PWKPhJ_G0022165
 protein coding gene Chr17:12196001-12233935 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021995
 protein coding gene Chr17:12144804-12181418 (+)
WSB/EiJ MGP_WSBEiJ_G0022476
 protein coding gene Chr17:13508502-13545759 (+)



Homology
more
  • Human Ortholog
    FAM120B, family with sequence similarity 120 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM120B, family with sequence similarity 120 member B
  • Synonyms
    CCPG, dJ894D12.1, KIAA1838, PGCC1, SAN1
  • Links
    NCBI Gene ID: 84498
    neXtProt AC: NX_Q96EK7
    UniProt: Q96EK7

  • Chr Location
    6q27; chr6:170290703-170407067 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
mice homozygous for a null allele exhibit increased DNA damage in cardiomyocytes associated with cardiomyocyte hypoplasia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    788
  • Tissues
    51
  • cDNA Data
    76
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67544 NCBI Gene Model | MGI Sequence Detail 37380 C57BL/6J ±  kb
    transcript NR_033586 RefSeq | MGI Sequence Detail 5831 C57BL/6  
    polypeptide Q6RI63 UniProt | EBI | MGI Sequence Detail 786 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000030837 constitutive coactivator of peroxisome proliferator-activated receptor gamma
      (term hierarchy)
    • InterPro Domains
      IPR026784 Constitutive coactivator of PPAR-gamma
      IPR029060 PIN-like domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 86
      Genomic 3
      cDNA 83

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2147037, MGI:2147063
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:318650 Liu Z, et al., San1 deficiency leads to cardiomyopathy due to excessive R-loop-associated DNA damage and cardiomyocyte hypoplasia. Biochim Biophys Acta Mol Basis Dis. 2021 Nov 1;1867(11):166237
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory