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Acadsb Gene Detail
Summary
  • Symbol
    Acadsb
  • Name
    acyl-Coenzyme A dehydrogenase, short/branched chain
  • Synonyms
    1300003O09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914135
    NCBI Gene: 66885
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:131012330-131047940 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 74.03 cM, cytoband F4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914135
 protein coding gene Chr7:131012330-131050673 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033105
 protein coding gene Chr7:136036837-136077477 (+)
A/J MGP_AJ_G0033087
 protein coding gene Chr7:132329012-132367216 (+)
AKR/J MGP_AKRJ_G0033019
 protein coding gene Chr7:135833119-135869522 (+)
BALB/cJ MGP_BALBcJ_G0033088
 protein coding gene Chr7:132011578-132047534 (+)
C3H/HeJ MGP_C3HHeJ_G0032802
 protein coding gene Chr7:135686737-135723996 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033599
 protein coding gene Chr7:141231130-141269354 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030570
 protein coding gene Chr7:133594421-133630840 (+)
CAST/EiJ MGP_CASTEiJ_G0032132
 protein coding gene Chr7:127536519-127577054 (+)
CBA/J MGP_CBAJ_G0032775
 protein coding gene Chr7:146117001-146152419 (+)
DBA/2J MGP_DBA2J_G0032927
 protein coding gene Chr7:130303668-130343784 (+)
FVB/NJ MGP_FVBNJ_G0032880
 protein coding gene Chr7:130169087-130204953 (+)
LP/J MGP_LPJ_G0033021
 protein coding gene Chr7:137530853-137570722 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032912
 protein coding gene Chr7:147040918-147076751 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033619
 protein coding gene Chr7:134824105-134863854 (+)
PWK/PhJ MGP_PWKPhJ_G0031838
 protein coding gene Chr7:123336879-123375665 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031684
 protein coding gene Chr7:121598097-121636973 (+)
WSB/EiJ MGP_WSBEiJ_G0032243
 protein coding gene Chr7:135727010-135763378 (+)



Homology
more
  • Human Ortholog
    ACADSB, acyl-CoA dehydrogenase short/branched chain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACADSB, acyl-CoA dehydrogenase short/branched chain
  • Synonyms
    2-MEBCAD, ACAD7, SBCAD
  • Links
    NCBI Gene ID: 36
    neXtProt AC: NX_P45954
    UniProt: P45954

  • Chr Location
    10q26.13; chr10:123008979-123058290 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    842
  • Tissues
    108
  • cDNA Data
    15
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66885 NCBI Gene Model | MGI Sequence Detail 35611 C57BL/6J ±  kb
    transcript NM_025826 RefSeq | MGI Sequence Detail 3348 C57BL/6  
    polypeptide Q9DBL1 UniProt | EBI | MGI Sequence Detail 432 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000003603 short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
      (term hierarchy)
    • EC
      1.3.8.5
    • InterPro Domains
      IPR006089 Acyl-CoA dehydrogenase, conserved site
      IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
      IPR009075 Acyl-CoA dehydrogenase/oxidase, C-terminal
      IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
      IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
      IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
      IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain
      IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 15
      Primer pair 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2142281
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 6
      Gene Ontology 13
      Phenotypes 3
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:338257 Peng MZ, et al., Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism. Cell Mol Life Sci. 2022 Jun 21;79(7):375
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory