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Fgf20 Gene Detail
Summary
  • Symbol
    Fgf20
  • Name
    fibroblast growth factor 20
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891346
    NCBI Gene: 80857
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:40732206-40740060 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 23.89 cM, cytoband B1.2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891346
 protein coding gene Chr8:40732206-40761372 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033550
 protein coding gene Chr8:39075678-39110020 (-)
A/J MGP_AJ_G0033530
 protein coding gene Chr8:37585848-37621838 (-)
AKR/J MGP_AKRJ_G0033454
 protein coding gene Chr8:38696928-38732154 (-)
BALB/cJ MGP_BALBcJ_G0033526
 protein coding gene Chr8:37676808-37713600 (-)
C3H/HeJ MGP_C3HHeJ_G0033238
 protein coding gene Chr8:39089207-39126228 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034042
 protein coding gene Chr8:40573858-40605512 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030991
 protein coding gene Chr8:34216689-34246543 (-)
CAST/EiJ MGP_CASTEiJ_G0032566
 protein coding gene Chr8:38613941-38644804 (-)
CBA/J MGP_CBAJ_G0033216
 protein coding gene Chr8:42247666-42288171 (-)
DBA/2J MGP_DBA2J_G0033369
 protein coding gene Chr8:37437059-37472774 (-)
FVB/NJ MGP_FVBNJ_G0033314
 protein coding gene Chr8:37016786-37046636 (-)
LP/J MGP_LPJ_G0033459
 protein coding gene Chr8:39099233-39136774 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033356
 protein coding gene Chr8:42030185-42071962 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034061
 protein coding gene Chr8:38894833-38931228 (-)
PWK/PhJ MGP_PWKPhJ_G0032275
 protein coding gene Chr8:36980377-37010941 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032107
 protein coding gene Chr8:38094782-38125711 (-)
WSB/EiJ MGP_WSBEiJ_G0032681
 protein coding gene Chr8:39086666-39118221 (-)



Homology
more
  • Human Ortholog
    FGF20, fibroblast growth factor 20
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FGF20, fibroblast growth factor 20
  • Synonyms
    FGF-20, RHDA2
  • Links
    NCBI Gene ID: 26281
    neXtProt AC: NX_Q9NP95
    UniProt: Q9NP95

  • Chr Location
    8p22; chr8:16992181-17002345 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human FGF20 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    3 images
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit imapired coclear lateral compartment differentiation and deafness without loss of vestibular function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    957
  • Tissues
    215
  • cDNA Data
    11
  • Literature Summary
    48
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 80857 NCBI Gene Model | MGI Sequence Detail 7855 C57BL/6J ±  kb
    transcript NM_030610 RefSeq | MGI Sequence Detail 1543 C57BL/6  
    polypeptide Q9ESL9 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 12
      Primer pair 6
      Other 3

      Microarray probesets 2
    References
    more
    • Summaries
      All 85
      Developmental Gene Expression 48
      Gene Ontology 9
      Phenotypes 27
    • Earliest
      J:76230 Hajihosseini MK, et al., Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev. 2002 Apr;113(1):79-83
    • Latest
      J:343094 Makela OJM, et al., Mesenchyme governs hair follicle induction. Development. 2023 Nov 15;150(22):dev202140
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory