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Ninj2 Gene Detail
Summary
  • Symbol
    Ninj2
  • Name
    ninjurin 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1352751
    NCBI Gene: 29862
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:120070315-120177300 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 56.90 cM, cytoband F1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    409 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1352751
protein coding gene Chr6:120070311-120177300 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031199
protein coding gene Chr6:122964245-123072623 (+)
A/J MGP_AJ_G0031168
protein coding gene Chr6:118228486-118341283 (+)
AKR/J MGP_AKRJ_G0031099
protein coding gene Chr6:121409444-121522442 (+)
BALB/cJ MGP_BALBcJ_G0031179
protein coding gene Chr6:118003997-118106860 (+)
C3H/HeJ MGP_C3HHeJ_G0030530
protein coding gene Chr6:62780680-62894678 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031637
protein coding gene Chr6:126083410-126215071 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030286
protein coding gene Chr6:121856699-121961812 (+)
CBA/J MGP_CBAJ_G0030862
protein coding gene Chr6:131107463-131226335 (+)
DBA/2J MGP_DBA2J_G0031018
protein coding gene Chr6:117127599-117229977 (+)
FVB/NJ MGP_FVBNJ_G0030970
protein coding gene Chr6:116244679-116354417 (+)
LP/J MGP_LPJ_G0031097
protein coding gene Chr6:122953914-123066205 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031004
protein coding gene Chr6:135123502-135235625 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031666
protein coding gene Chr6:121446197-121553256 (+)
PWK/PhJ MGP_PWKPhJ_G0030001
protein coding gene Chr6:116154116-116265594 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029830
protein coding gene Chr6:120170828-120272144 (+)
WSB/EiJ MGP_WSBEiJ_G0030369
protein coding gene Chr6:121728293-121844922 (+)



Homology
more
  • Human Ortholog
    NINJ2, ninjurin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NINJ2, ninjurin 2
  • Links
    NCBI Gene ID: 4815
    neXtProt AC: NX_Q9NZG7
    UniProt: Q9NZG7

  • Chr Location
    12p13.33; chr12:564296-663589 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 29862 NCBI Gene Model | MGI Sequence Detail 106986 C57BL/6J ±  kb
    transcript NM_016718 RefSeq | MGI Sequence Detail 849 C57BL/6  
    polypeptide Q9JL89 UniProt | EBI | MGI Sequence Detail 143 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 2
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:59126 Araki T, et al., Ninjurin2, a novel homophilic adhesion molecule, is expressed in mature sensory and enteric neurons and promotes neurite outgrowth. J Neurosci. 2000 Jan 1;20(1):187-95
    • Latest
      J:332575 Peng H, et al., NINJ2 deficiency inhibits preadipocyte differentiation and promotes insulin resistance through regulating insulin signaling. Obesity (Silver Spring). 2023 Jan;31(1):123-138

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    04/16/2024
    MGI 6.23
    The Jackson Laboratory