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Orc5 Gene Detail
Summary
  • Symbol
    Orc5
  • Name
    origin recognition complex, subunit 5
  • Synonyms
    MmORC5, mouse origin recognition complex 5, Orc5l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347044
    NCBI Gene: 26429
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:22691478-22755358 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 10.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    419 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347044
 protein coding gene Chr5:22691478-22755427 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029327
 protein coding gene Chr5:20054919-20114556 (-)
A/J MGP_AJ_G0029292
 protein coding gene Chr5:19426824-19486495 (-)
AKR/J MGP_AKRJ_G0029243
 protein coding gene Chr5:20169278-20233661 (-)
BALB/cJ MGP_BALBcJ_G0029304
 protein coding gene Chr5:19858136-19921769 (-)
C3H/HeJ MGP_C3HHeJ_G0029023
 protein coding gene Chr5:20253032-20311965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029757
 protein coding gene Chr5:21506155-21574266 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0028435
 protein coding gene Chr5:19558939-19620977 (-)
CBA/J MGP_CBAJ_G0028990
 protein coding gene Chr5:21780464-21840477 (-)
DBA/2J MGP_DBA2J_G0029142
 protein coding gene Chr5:19705668-19763020 (-)
FVB/NJ MGP_FVBNJ_G0029100
 protein coding gene Chr5:19108827-19167295 (-)
LP/J MGP_LPJ_G0029226
 protein coding gene Chr5:20469617-20527890 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029128
 protein coding gene Chr5:23009663-23078663 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029790
 protein coding gene Chr5:19772163-19830891 (-)
PWK/PhJ MGP_PWKPhJ_G0028158
 protein coding gene Chr5:18750155-18804096 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027991
 protein coding gene Chr5:19173141-19235300 (-)
WSB/EiJ MGP_WSBEiJ_G0028515
 protein coding gene Chr5:19868337-19926900 (-)



Homology
more
  • Human Ortholog
    ORC5, origin recognition complex subunit 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ORC5, origin recognition complex subunit 5
  • Synonyms
    ORC5L, ORC5P, ORC5T, PPP1R117
  • Links
    NCBI Gene ID: 5001
    neXtProt AC: NX_O43913
    UniProt: O43913

  • Chr Location
    7q22.1-q22.2; chr7:104126341-104208047 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    870
  • Tissues
    22
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26429 NCBI Gene Model | MGI Sequence Detail 63881 C57BL/6J ±  kb
transcript NM_011959 RefSeq | MGI Sequence Detail 2066 C57BL/6  
polypeptide Q9WUV0 UniProt | EBI | MGI Sequence Detail 435 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141023
References
more
  • Summaries
    All 44
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 8
    Phenotypes 17
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:339148 Jaremko MJ, et al., The dynamic nature of the human origin recognition complex revealed through five cryoEM structures. Elife. 2020 Aug 18;9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory