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Ift81 Gene Detail
Summary
  • Symbol
    Ift81
  • Name
    intraflagellar transport 81
  • Synonyms
    Cdv1, CDV-1R
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098597
    NCBI Gene: 12589
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:122688267-122752581 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 62.44 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    360 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098597
 protein coding gene Chr5:122678328-122752614 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030054
 protein coding gene Chr5:126186333-126255431 (-)
A/J MGP_AJ_G0030019
 protein coding gene Chr5:120960410-121025019 (-)
AKR/J MGP_AKRJ_G0029955
 protein coding gene Chr5:124854656-124919416 (-)
BALB/cJ MGP_BALBcJ_G0030030
 protein coding gene Chr5:122307558-122372986 (-)
C3H/HeJ MGP_C3HHeJ_G0029747
 protein coding gene Chr5:125487064-125553275 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030483
 protein coding gene Chr5:131038285-131124605 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027709
 protein coding gene Chr5:115567504-115631379 (-)
CAST/EiJ MGP_CASTEiJ_G0029156
 protein coding gene Chr5:124569518-124641220 (-)
CBA/J MGP_CBAJ_G0029717
 protein coding gene Chr5:136176711-136248808 (-)
DBA/2J MGP_DBA2J_G0029867
 protein coding gene Chr5:121017048-121081732 (-)
FVB/NJ MGP_FVBNJ_G0029823
 protein coding gene Chr5:120012253-120076086 (-)
LP/J MGP_LPJ_G0029956
 protein coding gene Chr5:126732720-126796478 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029854
 protein coding gene Chr5:139914102-139983082 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030524
 protein coding gene Chr5:124454882-124524906 (-)
PWK/PhJ MGP_PWKPhJ_G0028870
 protein coding gene Chr5:119799547-119865187 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028707
 protein coding gene Chr5:122152732-122225560 (-)
WSB/EiJ MGP_WSBEiJ_G0029231
 protein coding gene Chr5:125117276-125183651 (-)



Homology
more
  • Human Ortholog
    IFT81, intraflagellar transport 81
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFT81, intraflagellar transport 81
  • Synonyms
    CDV1, CDV-1, CDV1R, CDV-1R, DV1, SRTD19
  • Links
    NCBI Gene ID: 28981
    neXtProt AC: NX_Q8WYA0
    UniProt: Q8WYA0

  • Chr Location
    12q24.11; chr12:110124335-110218793 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human IFT81 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    46
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029469 Ensembl Gene Model | MGI Sequence Detail 64315 C57BL/6J ±  kb
    transcript ENSMUST00000031426 Ensembl | MGI Sequence Detail 2950 Not Applicable  
    polypeptide ENSMUSP00000031426 Ensembl | MGI Sequence Detail 676 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 46
      cDNA 46

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2141144
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 3
      Gene Ontology 14
      Phenotypes 15
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:333039 Zhang K, et al., Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis. Dev Cell. 2023 Jan 23;58(2):139-154.e8
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory