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Zfp69 Gene Detail
Summary
  • Symbol
    Zfp69
  • Name
    zinc finger protein 69
  • Synonyms
    KRAB2, LOC381549, Zfp63
  • Feature Type
    protein coding gene
  • IDs
    MGI:107794
    NCBI Gene: 381549
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:120787334-120808896 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 56.66 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    193 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107794
 protein coding gene Chr4:120786201-120808898 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028717
 protein coding gene Chr4:122233299-122247492 (-)
A/J MGP_AJ_G0028677
 protein coding gene Chr4:117406464-117422295 (-)
AKR/J MGP_AKRJ_G0028630
 protein coding gene Chr4:119997082-120011604 (-)
BALB/cJ MGP_BALBcJ_G0028700
 protein coding gene Chr4:118019462-118035372 (-)
C3H/HeJ MGP_C3HHeJ_G0028415
 protein coding gene Chr4:121524646-121540226 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029141
 protein coding gene Chr4:126837198-126856740 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026418
 protein coding gene Chr4:111452962-111467728 (-)
CAST/EiJ MGP_CASTEiJ_G0027846
 protein coding gene Chr4:118894086-118911475 (-)
CBA/J MGP_CBAJ_G0028382
 protein coding gene Chr4:130277030-130297988 (-)
DBA/2J MGP_DBA2J_G0028529
 protein coding gene Chr4:117984066-117998285 (-)
FVB/NJ MGP_FVBNJ_G0028495
 protein coding gene Chr4:116507345-116522457 (-)
LP/J MGP_LPJ_G0028629
 protein coding gene Chr4:122356125-122372255 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028523
 protein coding gene Chr4:135087950-135104235 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029178
 protein coding gene Chr4:121068555-121088108 (-)
PWK/PhJ MGP_PWKPhJ_G0027569
 protein coding gene Chr4:114928549-114947761 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027395
 protein coding gene Chr4:117484759-117504751 (-)
WSB/EiJ MGP_WSBEiJ_G0027926
 protein coding gene Chr4:121083888-121099945 (-)



Homology
more
  • Human Ortholog
    ZFP69, ZFP69 zinc finger protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZFP69, ZFP69 zinc finger protein
  • Synonyms
    ZFP69A, ZKSCAN23A, ZNF642, ZSCAN54A
  • Links
    NCBI Gene ID: 339559
    neXtProt AC: NX_Q49AA0
    UniProt: Q49AA0

  • Chr Location
    1p34.2; chr1:40477290-40496343 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    22
  • cDNA Data
    10
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000064141 Ensembl Gene Model | MGI Sequence Detail 21563 C57BL/6J ±  kb
    transcript ENSMUST00000106280 Ensembl | MGI Sequence Detail 2362 Not Applicable  
    polypeptide ENSMUSP00000101887 Ensembl | MGI Sequence Detail 587 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      Genomic 1
      cDNA 10
      Primer pair 1

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGD-MRK-36371, MGI:2685875
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:29678 Bellefroid EJ, et al., Emergence of the ZNF91 Kruppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea. Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10757-61
    • Latest
      J:226423 Chung B, et al., The diabetes gene Zfp69 modulates hepatic insulin sensitivity in mice. Diabetologia. 2015 Oct;58(10):2403-13
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory