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Cct5 Gene Detail
Summary
  • Symbol
    Cct5
  • Name
    chaperonin containing TCP1 subunit 5
  • Synonyms
    Ccte, mKIAA0098, TCPE
  • Feature Type
    protein coding gene
  • IDs
    MGI:107185
    NCBI Gene: 12465
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:31590946-31601950 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 13.02 cM, cytoband B3.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    101 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107185
 protein coding gene Chr15:31590946-31601992 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021768
 protein coding gene Chr15:29848770-29859961 (-)
A/J MGP_AJ_G0021729
 protein coding gene Chr15:28645405-28656451 (-)
AKR/J MGP_AKRJ_G0021706
 protein coding gene Chr15:29376581-29389216 (-)
BALB/cJ MGP_BALBcJ_G0021735
 protein coding gene Chr15:28652241-28663288 (-)
C3H/HeJ MGP_C3HHeJ_G0021510
 protein coding gene Chr15:29399068-29410115 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022174
 protein coding gene Chr15:31038547-31053189 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019712
 protein coding gene Chr15:26738481-26749522 (-)
CAST/EiJ MGP_CASTEiJ_G0021026
 protein coding gene Chr15:29892349-29903508 (-)
CBA/J MGP_CBAJ_G0021479
 protein coding gene Chr15:31919739-31930786 (-)
DBA/2J MGP_DBA2J_G0021603
 protein coding gene Chr15:28452477-28463524 (-)
FVB/NJ MGP_FVBNJ_G0021581
 protein coding gene Chr15:27975248-27986295 (-)
LP/J MGP_LPJ_G0021672
 protein coding gene Chr15:29718607-29731114 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021606
 protein coding gene Chr15:34897727-34908754 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022197
 protein coding gene Chr15:29631840-29642887 (-)
PWK/PhJ MGP_PWKPhJ_G0020770
 protein coding gene Chr15:28614987-28626122 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020608
 protein coding gene Chr15:29418325-29430684 (-)
WSB/EiJ MGP_WSBEiJ_G0021082
 protein coding gene Chr15:29578399-29592728 (-)



Homology
more
  • Human Ortholog
    CCT5, chaperonin containing TCP1 subunit 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCT5, chaperonin containing TCP1 subunit 5
  • Synonyms
    CCTE, CCT-epsilon, HEL-S-69, PNAS-102, TCP-1-epsilon
  • Links
    NCBI Gene ID: 22948
    neXtProt AC: NX_P48643
    UniProt: P48643

  • Chr Location
    5p15.2; chr5:10249921-10266412 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    2
  • cDNA Data
    462
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022234 Ensembl Gene Model | MGI Sequence Detail 11005 C57BL/6J ±  kb
    transcript ENSMUST00000022842 Ensembl | MGI Sequence Detail 1853 Not Applicable  
    polypeptide ENSMUSP00000022842 Ensembl | MGI Sequence Detail 541 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000005153 T-complex protein 1 subunit epsilon
      (term hierarchy)
    • InterPro Domains
      IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
      IPR002423 Chaperonin Cpn60/GroEL/TCP-1 family
      IPR002194 Chaperonin TCP-1, conserved site
      IPR027409 GroEL-like apical domain superfamily
      IPR027413 GroEL-like equatorial domain superfamily
      IPR012718 T-complex protein 1, epsilon subunit
      IPR027410 TCP-1-like chaperonin intermediate domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 463
      cDNA 462
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-35646
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 2
      Gene Ontology 13
      Phenotypes 14
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:205312 Tarkar A, et al., DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Sep;45(9):995-1003
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory