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Gene Expression Data
Assay Details
Assay
Reference: J:91216 Kolterud A, et al., Lhx2 is expressed in the septum transversum mesenchyme that becomes an integral part of the liver and the formation of these cells is independent of functional Lhx2. Gene Expr Patterns. 2004 Sep;4(5):521-8
Assay type: RNA in situ
MGI Accession ID: MGI:3052985
Gene symbol: Lhx2
Gene name: LIM homeobox protein 2
Probe: Lhx2 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1D,E: embryonic day 8.0 (more )
Note: 8 somites. Double labeled: blue (D)/green (E) - Lhx2; red - Foxa2 (assay MGI:3053048).
Structure Level Pattern Image Note
TS12: foregut diverticulum endoderm Absent 1E , 1D
Specimen 1H: embryonic day 9.0 (more )
Note: 16 somites.
Structure Level Pattern Image Note
TS14: septum transversum Present 1H
Specimen 1I,J: embryonic day 9.0 (more )
Note: 16 somites. Double labeled: blue (I)/green (J) - Lhx2; red - Foxa2 (assay MGI:3053048).
Structure Level Pattern Image Note
TS14: septum transversum hepatic component Present 1J , 1I
Specimen 1K,L: embryonic day 9.5 (more )
Note: 22 somites. Double labeled: blue (K)/green (L) - Lhx2; red - Foxa2 (assay MGI:3053048).
Structure Level Pattern Image Note
TS15: septum transversum hepatic component Present 1L , 1K
Specimen 1M,N: embryonic day 9.5 (more )
Note: 25 somites. Double labeled: blue (M)/green (N) - Lhx2; red - Foxa2 (assay MGI:3053048).
Structure Level Pattern Image Note
TS15: septum transversum hepatic component Present 1M , 1N
Specimen 1P,Q: embryonic day 9.5 (more )
Note: Triple labeled: blue - Lhx2; magenta/brown - Bmp4 (assay MGI:3052984); pink/light red - Foxa2 (assay MGI:3053048).
Structure Level Pattern Image Note
TS15: septum transversum hepatic component Present 1Q , 1P
Specimen 2A: embryonic day 10.5 (more )
Note: Double labeled: blue - Lhx2; brown - Alb (assay MGI:3053033).
Structure Level Pattern Image Note
TS17: liver Present 2A
Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 2B Expression is surrounding each liver lobe and is scattered within each lobe.
Specimen 2C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 2C Expression surrounds each liver lobe and is as a discontinuous layer, close to or at, the outermost cell layer of the liver.
Specimen 2D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: liver Present Regionally restricted 2D Expression is surrounding each liver lobe and is scattered within each lobe.
Specimen 2E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: intraembryonic coelom Present Regionally restricted 2E Expression is in a subpopulation of cells in the diaphragm.
Specimen 2F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Present Spotted 2F
Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Present Regionally restricted Few, if any, positive cells could be detected among the cells surrounding each liver lobe.
Specimen 3C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: liver Present 3C
Specimen 3F: embryonic day 10.5; Lhx2tm1Dra/Lhx2tm1Dra (more )
Structure Level Pattern Image Note
TS17: liver Present 3F Expression in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory