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Cass4 Gene Detail
Summary
  • Symbol
    Cass4
  • Name
    Cas scaffolding protein family member 4
  • Synonyms
    F730031O20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444482
    NCBI Gene: 320664
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:172235714-172275677 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 94.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1336 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444482
 protein coding gene Chr2:172234998-172275677 (+)
129S1/SvImJ ENSMUSG00200040063
 protein coding gene Chr2:169159761-169199993 (+)
A/J ENSMUSG00195024102
 protein coding gene Chr2:169488067-169528300 (+)
AKR/J ENSMUSG00220032015
 protein coding gene Chr2:168783813-168824041 (+)
BALB/cJ ENSMUSG00180033854
 protein coding gene Chr2:168934331-168974279 (+)
C3H/HeJ ENSMUSG00175038682
 protein coding gene Chr2:169704077-169744030 (+)
C57BL/6NJ ENSMUSG00215026574
 protein coding gene Chr2:169126426-169166397 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024737
 protein coding gene Chr2:164336651-164376710 (+)
CAST/EiJ ENSTCUG00005008615
 protein coding gene Chr2:168028464-168068275 (+)
CBA/J ENSMUSG00210038506
 protein coding gene Chr2:169614356-169654299 (+)
DBA/2J ENSMUSG00185023710
 protein coding gene Chr2:169327916-169367860 (+)
FVB/NJ ENSMUSG00205017189
 protein coding gene Chr2:168383888-168423784 (+)
JF1/MsJ ENSUMUG00000019886
 protein coding gene Chr2:169013947-169053897 (+)
LP/J ENSMUSG00230010302
 protein coding gene Chr2:170896233-170936459 (+)
NOD/ShiLtJ ENSMUSG00190037548
 protein coding gene Chr2:169014611-169054553 (+)
NZO/HlLtJ ENSMUSG00225002494
 protein coding gene Chr2:178890298-178930232 (+)
PWK/PhJ ENSLUMG00010032948
 protein coding gene Chr2:168902499-168942403 (+)
SPRET/EiJ ENSMSPG00010024587
 protein coding gene Chr2:171659623-171699973 (+)
WSB/EiJ ENSIUOG00005022144
 protein coding gene Chr2:168756902-168796838 (+)



Homology
more
  • Human Ortholog
    CASS4, Cas scaffold protein family member 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CASS4, Cas scaffold protein family member 4
  • Synonyms
    C20orf32, CAS4, HEFL, HEPL
  • Links
    NCBI Gene ID: 57091
    UniProt: Q9NQ75

  • Chr Location
    20q13.31; chr20:56412036-56460387 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    4
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074570 Ensembl Gene Model | MGI Sequence Detail 39964 C57BL/6J ±  kb
transcript ENSMUST00000109136 Ensembl | MGI Sequence Detail 2702 Not Applicable  
polypeptide ENSMUSP00000104764 Ensembl | MGI Sequence Detail 804 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory