About   Help   FAQ
Dhrs9 Gene Detail
Summary
  • Symbol
    Dhrs9
  • Name
    dehydrogenase/reductase 9
  • Synonyms
    C730025I08Rik, dehydrogenase/reductase (SDR family) member 9, Rdh15
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442798
    NCBI Gene: 241452
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:69210806-69233430 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 40.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    800 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442798
protein coding gene Chr2:69210789-69234877 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025798
protein coding gene Chr2:69344347-69371780 (+)
A/J MGP_AJ_G0025775
protein coding gene Chr2:66666595-66690580 (+)
AKR/J MGP_AKRJ_G0025744
protein coding gene Chr2:68462629-68486525 (+)
BALB/cJ MGP_BALBcJ_G0025770
protein coding gene Chr2:66827712-66851668 (+)
C3H/HeJ MGP_C3HHeJ_G0025530
protein coding gene Chr2:68696284-68720134 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026217
protein coding gene Chr2:71444951-71474178 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023620
protein coding gene Chr2:63881356-63905371 (+)
CAST/EiJ MGP_CASTEiJ_G0024994
protein coding gene Chr2:68800083-68828607 (+)
CBA/J MGP_CBAJ_G0025510
protein coding gene Chr2:74052171-74081494 (+)
DBA/2J MGP_DBA2J_G0025641
protein coding gene Chr2:66304287-66328369 (+)
FVB/NJ MGP_FVBNJ_G0025604
protein coding gene Chr2:65678800-65702690 (+)
LP/J MGP_LPJ_G0025730
protein coding gene Chr2:69184766-69214343 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025633
protein coding gene Chr2:76100204-76126432 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026274
protein coding gene Chr2:68550836-68574728 (+)
PWK/PhJ MGP_PWKPhJ_G0024735
protein coding gene Chr2:66131787-66154845 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024542
protein coding gene Chr2:68775816-68799660 (+)
WSB/EiJ MGP_WSBEiJ_G0025062
protein coding gene Chr2:68978243-69006468 (+)



Homology
more
  • Human Ortholog
    DHRS9, dehydrogenase/reductase 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DHRS9, dehydrogenase/reductase 9
  • Synonyms
    3-alpha-HSD, 3ALPHA-HSD, hRoDH-E2, RDH15, RDHL, RDH-TBE, RDHTBE, RETSDR8, SDR9C4
  • Links
    NCBI Gene ID: 10170
    neXtProt AC: NX_Q9BPW9
    UniProt: Q9BPW9

  • Chr Location
    2q31.1; chr2:169064789-169096167 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    4
  • Genomic Mutations
    1 involving Dhrs9
  • Find Mice (IMSR)
Mice homozygous for a null allele exhibit reduced LTB4 ad RvD1 dehydrogenase activities in the skin, lung, and tracheal microsomes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 241452 NCBI Gene Model | MGI Sequence Detail 22625 C57BL/6J ±  kb
transcript NM_175512 RefSeq | MGI Sequence Detail 2817 C57BL/6  
polypeptide Q58NB6 UniProt | EBI | MGI Sequence Detail 319 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory