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Nfrkb Gene Detail
Summary
  • Symbol
    Nfrkb
  • Name
    nuclear factor related to kappa B binding protein
  • Synonyms
    A530090G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442410
    NCBI Gene: 235134
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:31297488-31332629 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 16.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    843 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442410
 protein coding gene Chr9:31297476-31332629 (+)
129S1/SvImJ ENSMUSG00200007610
 protein coding gene Chr9:28296196-28331344 (+)
A/J ENSMUSG00195005582
 protein coding gene Chr9:28108195-28143356 (+)
AKR/J ENSMUSG00220010234
 protein coding gene Chr9:28137914-28173061 (+)
BALB/cJ ENSMUSG00180006447
 protein coding gene Chr9:28236662-28271818 (+)
C3H/HeJ ENSMUSG00175018873
 protein coding gene Chr9:28217173-28252325 (+)
C57BL/6NJ ENSMUSG00215007504
 protein coding gene Chr9:28193044-28228193 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031939
 protein coding gene Chr9:27179780-27215221 (+)
CAST/EiJ ENSTCUG00005018821
 protein coding gene Chr9:28196086-28231116 (+)
CBA/J ENSMUSG00210022078
 protein coding gene Chr9:28247490-28282618 (+)
DBA/2J ENSMUSG00185002192
 protein coding gene Chr9:28289681-28324802 (+)
FVB/NJ ENSMUSG00205003796
 protein coding gene Chr9:28591623-28626789 (+)
JF1/MsJ ENSUMUG00000009810
 protein coding gene Chr9:28473726-28508603 (+)
LP/J ENSMUSG00230004274
 protein coding gene Chr9:28726515-28761660 (+)
NOD/ShiLtJ ENSMUSG00190005719
 protein coding gene Chr9:28328910-28364057 (+)
NZO/HlLtJ ENSMUSG00225014837
 protein coding gene Chr9:28705378-28740498 (+)
PWK/PhJ ENSLUMG00010008822
 protein coding gene Chr9:28328890-28363867 (+)
SPRET/EiJ ENSMSPG00010002115
 protein coding gene Chr9:28691218-28728347 (+)
WSB/EiJ ENSIUOG00005015202
 protein coding gene Chr9:27769933-27805084 (+)



Homology
more
  • Human Ortholog
    NFRKB, nuclear factor related to kappaB binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NFRKB, nuclear factor related to kappaB binding protein
  • Synonyms
    INO80G
  • Links
    NCBI Gene ID: 4798
    UniProt: Q6P4R8

  • Chr Location
    11q24.3; chr11:129863636-129895590 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    105
  • cDNA Data
    101
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042185 Ensembl Gene Model | MGI Sequence Detail 35142 C57BL/6J ±  kb
transcript ENSMUST00000086167 Ensembl | MGI Sequence Detail 5161 Not Applicable  
polypeptide ENSMUSP00000083341 Ensembl | MGI Sequence Detail 1296 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000011183 nuclear factor related to kappa-B-binding protein
    (term hierarchy)
  • InterPro Domains
    IPR044867 DEUBAD domain
    IPR038106 NFRKB winged helix-like domain superfamily
    IPR024867 Nuclear factor related to kappa-B-binding protein
    IPR057748 Nuclear factor related to kappa-B-binding protein, second winged helix domain
    IPR025220 Nuclear factor related to kappa-B-binding protein, winged helix-like domain
  • GlyGen
    Q6PIJ4 30 sites, 1 O-linked glycan (28 sites)
Molecular
Reagents
less
  • All nucleic 102
    cDNA 101
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory