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Gene Expression Data
Assay Details
Assay
Reference: J:65633 Vasiliauskas D, et al., Expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of bHLH transcription factors. Mech Dev. 2000 Nov;98(1-2):133-7
Assay type: RNA in situ
MGI Accession ID: MGI:2387000
Gene symbol: Hes6
Gene name: hairy and enhancer of split 6
Probe: IMAGE clone 385069
Probe preparation: Antisense RNA
Results
Specimen 2A E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: olfactory placode Present 2A
TS15: otocyst mesenchyme Present 2A
TS15: trigeminal preganglion Present 2A
TS15: lens placode Absent 2A
TS15: central nervous system Present Regionally restricted 2A There is expression in all neurogenic placodes, including the epibranchial placodes.
TS15: embryo mesenchyme Present Regionally restricted 2A There is expression in the mesenchyme underlying the neurogenic placodes.
TS15: otocyst Present Regionally restricted 2A Expression is restricted to the anterior-ventral region.
Specimen 2B E9.75: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: facio-acoustic ganglion complex Present 2B
TS16: nasal pit Present 2B
TS16: otocyst mesenchyme Present 2B
TS16: central nervous system Present Regionally restricted 2B Expression is in all neurogenic placodes.
TS16: embryo mesenchyme Present Regionally restricted 2B Expression is in mesenchyme underlying the neurogenic placodes.
TS16: otocyst Present Regionally restricted 2B Expression is restricted to the anterior-ventral region.
Specimen 2C 10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nasal pit Present 2C
TS17: otocyst Present Regionally restricted 2C Expression is in the anterior-ventral region.
TS17: central nervous system Present Regionally restricted 2C Expression is in all neurogenic placodes.
TS17: embryo mesenchyme Present Regionally restricted 2C Expression is in cells adjacent to the neurogenic placodes.
TS17: lens pit Absent 2C
TS17: optic stalk Present 2C
Specimen 2D 11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: branchial arch mesenchyme Present 2D
TS19: optic stalk Present 2D
Specimen 2E E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch ectoderm Present Regionally restricted 2E Expression is in the ectodermal placode.
TS15: 2nd branchial arch mesenchyme Present Regionally restricted 2E Expression is in the mesenchyme underlying the ectodermal placode.
Specimen 2F E9.75: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: 2nd branchial arch ectoderm Present Regionally restricted 2F Expression is in the placode.
TS16: 2nd branchial arch mesenchyme Present Regionally restricted 2F Expression is in the cells underlying the placode and extends dorsally compared to E9.5.
Specimen 2G E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 2nd branchial groove ectoderm Present Regionally restricted 2G Expression is in the placode.
TS17: 2nd branchial membrane ectoderm Present Regionally restricted 2G Expression is in the placode.
TS17: 2nd branchial arch mesenchyme Present Regionally restricted 2G Expression is in the mesenchyme underlying the ectodermal placode.
TS17: glossopharyngeal ganglion Present 2G
Specimen 2H 9.75: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: otocyst epithelium Present Regionally restricted 2H Expression is in the anteroventral aspect.
TS16: otocyst mesenchyme Present Regionally restricted 2H Expression is in the cells that are underlying the anteroventral epithelial expression.
Specimen 2I 11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 2I Expression is in the anteroventral aspect.
TS19: acoustic ganglion Present 2I
TS19: facial ganglion Absent 2I
Specimen 2J 10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nasal pit Present 2J
TS17: optic stalk Present 2J
Specimen 2K E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nasal pit Present 2K
TS19: optic stalk Present 2K
TS19: trigeminal ganglion Present 2K
Specimen 2L E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present Regionally restricted 2L Expression is in a dorsal and ventral anterioposterior stripe.
TS17: midbrain Present Regionally restricted 2L Expression is in a dorsal and ventral anterioposterior stripe.
TS17: hindbrain Present Regionally restricted 2L Expression is in a dorsal and ventral anterioposterior stripe. The expression is downregulated in rhombomeres 2-4.
Specimen 2M E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Present Regionally restricted 2M Expression is in a dorsal and ventral anterioposterior stripe.
TS19: midbrain Present Regionally restricted 2M Expression is in a dorsal and ventral anterioposterior stripe.
TS19: hindbrain Present Regionally restricted 2M Expression is in a dorsal and ventral anterioposterior stripe. The expression is downregulated in rhombomeres 2-4.
Specimen 2N E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 2N There is an anterior boundary of expression at the diencephalon.
TS15: future hindbrain Present Regionally restricted 2N There is a sharp anterior boundary at the isthmic region.
Specimen 2O E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 2O Expression is rostral.
TS17: nasal pit Present 2O Expression is in the olfactory placode.
TS17: optic stalk Present 2O
Specimen 2P E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 2P There is an anterior boundary at the isthmus.
TS17: midbrain Present Regionally restricted 2P There is an anterior boundary at the diencephalon.
TS17: telencephalon Present Regionally restricted 2P Expression is rostral.
TS17: optic stalk Present 2P
Specimen 2Q E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2Q There is an anterior border of expression at the isthmus.
TS19: midbrain Present Regionally restricted 2Q There is an anterior border of expression at the diencephalon.
TS19: telencephalon Present Regionally restricted 2Q Expression is rostral.
TS19: optic stalk Present 2Q
Specimen 3A E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 3A
TS17: forelimb bud Present 3A
TS17: future spinal cord Present 3A
TS17: hindlimb bud Present 3A
TS17: trunk dermomyotome Present Regionally restricted 3A Expression is in the myotome.
Specimen 3B E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 3B
TS19: forelimb bud Present 3B
TS19: future spinal cord Present 3B
TS19: hindlimb bud Present 3B
TS19: trunk dermomyotome Present Regionally restricted 3B Expression is in the myotome.
Specimen 3C E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 3C Expression is in the dorsal-most region and in the ventral half.
Specimen 3D E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3D There are ventral and dorsal domains of expression as well as several dorsoventrally-resricted bands at different levels.
TS17: trunk dermomyotome Present Regionally restricted 3D Expression is in the myotome.
TS17: dorsal root ganglion Present 3D
Specimen 3E E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk dermomyotome Present Regionally restricted 3E Expression is in the myotome.
TS19: dorsal root ganglion Present 3E
TS19: neural tube Present 3E
Specimen 3F E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk dermomyotome Present Regionally restricted 3F Expression is in the myotome.
TS19: dorsal root ganglion Present 3F
TS19: neural tube Present 3F
Specimen 4A E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4A Expression is in two domains, dorsal and ventral, in the central area underlying the surface ectoderm.
Specimen 4B E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future arm mesenchyme Present Regionally restricted 4B The dorsal and ventral expression domains elongate with the limb.
TS19: handplate mesenchyme Present Regionally restricted 4B The dorsal and ventral expression domains elongate with the limb.
Specimen 4C E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future arm mesenchyme Present Regionally restricted 4C The dorsal and ventral expression domains elongate with the limb.
TS19: handplate mesenchyme Present Regionally restricted 4C The dorsal and ventral expression domains elongate with the limb.
Specimen 4D E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 4D Expression is in the future muscle masses and forming tendons.
Specimen 4E E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 4E Expression is in the future muscle masses and forming tendons.
Specimen 4F E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 4F Expression is in the future muscle masses and forming tendons.
Specimen 4G E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 4G Expression is in the future muscle masses and forming tendons.
Specimen 4H 10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4H Expression is in a dorsal and ventral domain underlying the surface ectoderm.
Specimen 4I E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future arm mesenchyme Present Regionally restricted 4I There are dorsal and ventral domains underlying the surface ectoderm.
TS19: handplate mesenchyme Present Regionally restricted 4I There are dorsal and ventral domains underlying the surface ectoderm.
Specimen 4J E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 4J Expression is in the future muscle masses and forming tendons.
Specimen 4K E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 4K Expression is in the forming tendons.
Specimen Not Shown E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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