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Klhdc4 Gene Detail
Summary
  • Symbol
    Klhdc4
  • Name
    kelch domain containing 4
  • Synonyms
    G430025P05Rik, MGC:19372
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384569
    NCBI Gene: 234825
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:122523052-122556308 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 70.76 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1114 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384569
 protein coding gene Chr8:122523047-122556322 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034216
 protein coding gene Chr8:125326240-125356939 (-)
A/J MGP_AJ_G0034196
 protein coding gene Chr8:120120965-120152804 (-)
AKR/J MGP_AKRJ_G0034123
 protein coding gene Chr8:123642704-123673878 (-)
BALB/cJ MGP_BALBcJ_G0034190
 protein coding gene Chr8:120325355-120354089 (-)
C3H/HeJ MGP_C3HHeJ_G0033901
 protein coding gene Chr8:124343217-124371496 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034710
 protein coding gene Chr8:129501964-129529621 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031652
 protein coding gene Chr8:112955628-112987089 (-)
CAST/EiJ MGP_CASTEiJ_G0033228
 protein coding gene Chr8:124393289-124422563 (-)
CBA/J MGP_CBAJ_G0033874
 protein coding gene Chr8:134266487-134294234 (-)
DBA/2J MGP_DBA2J_G0034030
 protein coding gene Chr8:119313316-119341423 (-)
FVB/NJ MGP_FVBNJ_G0033973
 protein coding gene Chr8:118432992-118461980 (-)
LP/J MGP_LPJ_G0034119
 protein coding gene Chr8:125455254-125483082 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034020
 protein coding gene Chr8:136485751-136518735 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034728
 protein coding gene Chr8:123815175-123845705 (-)
PWK/PhJ MGP_PWKPhJ_G0032930
 protein coding gene Chr8:119128657-119155552 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032770
 protein coding gene Chr8:122532260-122558252 (-)
WSB/EiJ MGP_WSBEiJ_G0033344
 protein coding gene Chr8:124570105-124602548 (-)



Homology
more
  • Human Ortholog
    KLHDC4, kelch domain containing 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLHDC4, kelch domain containing 4
  • Links
    NCBI Gene ID: 54758
    neXtProt AC: NX_Q8TBB5
    UniProt: Q8TBB5

  • Chr Location
    16q24.2; chr16:87696485-87765992 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    49
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040263 Ensembl Gene Model | MGI Sequence Detail 33257 C57BL/6J ±  kb
transcript ENSMUST00000045884 Ensembl | MGI Sequence Detail 2078 Not Applicable  
polypeptide ENSMUSP00000043439 Ensembl | MGI Sequence Detail 584 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 49

    Microarray probesets 5
Other
Accession IDs
less
MGI:1889338, MGI:2142740
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory