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Celf3 Gene Detail
Summary
  • Symbol
    Celf3
  • Name
    CUGBP, Elav-like family member 3
  • Synonyms
    4930415M08Rik, BRUNOL1, CAGH4, ERDA4, Tnrc4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926034
    NCBI Gene: 78784
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:94385602-94399505 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.73 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    309 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926034
protein coding gene Chr3:94385581-94405822 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027553
protein coding gene Chr3:95057305-95071174 (+)
A/J MGP_AJ_G0027512
protein coding gene Chr3:92166055-92179795 (+)
AKR/J MGP_AKRJ_G0027480
protein coding gene Chr3:94260874-94274746 (+)
BALB/cJ MGP_BALBcJ_G0027523
protein coding gene Chr3:91875702-91889595 (+)
C3H/HeJ MGP_C3HHeJ_G0027259
protein coding gene Chr3:94564816-94579706 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027972
protein coding gene Chr3:98642057-98657217 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025314
protein coding gene Chr3:88656015-88670157 (+)
CAST/EiJ MGP_CASTEiJ_G0026707
protein coding gene Chr3:93901123-93917095 (+)
CBA/J MGP_CBAJ_G0027235
protein coding gene Chr3:102144331-102158085 (+)
DBA/2J MGP_DBA2J_G0027374
protein coding gene Chr3:91429619-91443653 (+)
FVB/NJ MGP_FVBNJ_G0027344
protein coding gene Chr3:89527239-89542015 (+)
LP/J MGP_LPJ_G0027482
protein coding gene Chr3:96364162-96379043 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027371
protein coding gene Chr3:108372167-108388951 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028026
protein coding gene Chr3:93936174-93950060 (+)
PWK/PhJ MGP_PWKPhJ_G0026435
protein coding gene Chr3:91318981-91332479 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026256
protein coding gene Chr3:92279600-92293427 (+)
WSB/EiJ MGP_WSBEiJ_G0026790
protein coding gene Chr3:94290119-94303848 (+)



Homology
more
  • Human Ortholog
    CELF3, CUGBP Elav-like family member 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CELF3, CUGBP Elav-like family member 3
  • Synonyms
    BRUNOL1, CAGH4, ERDA4, ETR-1, TNRC4
  • Links
    NCBI Gene ID: 11189
    neXtProt AC: NX_Q5SZQ8
    UniProt: Q5SZQ8

  • Chr Location
    1q21.3; chr1:151700058-151716803 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a null mutation display reduced sperm counts and motility but are fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028137 Ensembl Gene Model | MGI Sequence Detail 13904 C57BL/6J ±  kb
transcript ENSMUST00000200342 Ensembl | MGI Sequence Detail 3173 Not Applicable  
polypeptide ENSMUSP00000143344 Ensembl | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 32
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 38
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory