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Ddx52 Gene Detail
Summary
  • Symbol
    Ddx52
  • Name
    DExD box helicase 52
  • Synonyms
    2700029C06Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 52, ROK1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925644
    NCBI Gene: 78394
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83832888-83853914 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.24 cM, cytoband B5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925644
 protein coding gene Chr11:83831659-83853914 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018863
 protein coding gene Chr11:85333256-85355217 (+)
A/J MGP_AJ_G0018830
 protein coding gene Chr11:82092394-82114171 (+)
AKR/J MGP_AKRJ_G0018800
 protein coding gene Chr11:84514335-84535332 (+)
BALB/cJ MGP_BALBcJ_G0018803
 protein coding gene Chr11:82472977-82496499 (+)
C3H/HeJ MGP_C3HHeJ_G0018617
 protein coding gene Chr11:84566206-84588101 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019255
 protein coding gene Chr11:87916740-87942943 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016888
 protein coding gene Chr11:79182983-79203736 (+)
CAST/EiJ MGP_CASTEiJ_G0018172
 protein coding gene Chr11:85192679-85218698 (+)
CBA/J MGP_CBAJ_G0018588
 protein coding gene Chr11:91697609-91720862 (+)
DBA/2J MGP_DBA2J_G0018696
 protein coding gene Chr11:81669803-81691287 (+)
FVB/NJ MGP_FVBNJ_G0018685
 protein coding gene Chr11:81140471-81161418 (+)
LP/J MGP_LPJ_G0018766
 protein coding gene Chr11:85868272-85892014 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018712
 protein coding gene Chr11:91844975-91865935 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019295
 protein coding gene Chr11:84795544-84817655 (+)
PWK/PhJ MGP_PWKPhJ_G0017941
 protein coding gene Chr11:82421057-82445384 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017733
 protein coding gene Chr11:84323173-84347946 (+)
WSB/EiJ MGP_WSBEiJ_G0018223
 protein coding gene Chr11:84638262-84660248 (+)



Homology
more
  • Human Ortholog
    DDX52, DExD-box helicase 52
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DDX52, DExD-box helicase 52
  • Synonyms
    HUSSY19, ROK1
  • Links
    NCBI Gene ID: 11056
    UniProt: Q9Y2R4

  • Chr Location
    17q12; chr17:37609739-37643446 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    4
  • cDNA Data
    121
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020677 Ensembl Gene Model | MGI Sequence Detail 21027 C57BL/6J ±  kb
    transcript ENSMUST00000049257 Ensembl | MGI Sequence Detail 3194 Not Applicable  
    polypeptide ENSMUSP00000048802 Ensembl | MGI Sequence Detail 598 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 123
      cDNA 121
      Primer pair 1
      Other 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 16
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory