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Nipal2 Gene Detail
Summary
  • Symbol
    Nipal2
  • Name
    NIPA-like domain containing 2
  • Synonyms
    9330161F08Rik, Npal2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924488
    NCBI Gene: 223473
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:34572945-34679358 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 14.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4057 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924488
 protein coding gene Chr15:34572942-34679739 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021783
 protein coding gene Chr15:32892363-33020543 (-)
A/J MGP_AJ_G0021744
 protein coding gene Chr15:31635277-31740965 (-)
AKR/J MGP_AKRJ_G0021722
 protein coding gene Chr15:32495407-32609270 (-)
BALB/cJ MGP_BALBcJ_G0021750
 protein coding gene Chr15:31649158-31756099 (-)
C3H/HeJ MGP_C3HHeJ_G0021525
 protein coding gene Chr15:32474153-32589572 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022189
 protein coding gene Chr15:34152605-34265574 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019727
 protein coding gene Chr15:29519438-29629327 (-)
CAST/EiJ MGP_CASTEiJ_G0021041
 protein coding gene Chr15:32885295-32993271 (-)
CBA/J MGP_CBAJ_G0021494
 protein coding gene Chr15:35213649-35331248 (-)
DBA/2J MGP_DBA2J_G0021618
 protein coding gene Chr15:31442632-31552300 (-)
FVB/NJ MGP_FVBNJ_G0021596
 protein coding gene Chr15:30894032-31001498 (-)
LP/J MGP_LPJ_G0021687
 protein coding gene Chr15:32785065-32918046 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021621
 protein coding gene Chr15:38210917-38345485 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022212
 protein coding gene Chr15:32672283-32781169 (-)
PWK/PhJ MGP_PWKPhJ_G0020785
 protein coding gene Chr15:31487371-31605520 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020623
 protein coding gene Chr15:32371665-32486231 (-)
WSB/EiJ MGP_WSBEiJ_G0021097
 protein coding gene Chr15:32645960-32758320 (-)



Homology
more
  • Human Ortholog
    NIPAL2, NIPA like domain containing 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NIPAL2, NIPA like domain containing 2
  • Synonyms
    NPAL2, SLC57A4
  • Links
    NCBI Gene ID: 79815
    UniProt: Q9H841

  • Chr Location
    8q22.2; chr8:98189826-98294393 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    1
  • cDNA Data
    43
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038879 Ensembl Gene Model | MGI Sequence Detail 106414 C57BL/6J ±  kb
    transcript ENSMUST00000040791 Ensembl | MGI Sequence Detail 4331 Not Applicable  
    polypeptide ENSMUSP00000038922 Ensembl | MGI Sequence Detail 383 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 43
      cDNA 43

      Microarray probesets 2
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory