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Wdr75 Gene Detail
Summary
  • Symbol
    Wdr75
  • Name
    WD repeat domain 75
  • Synonyms
    1300003A18Rik, 2410118I19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920924
    NCBI Gene: 73674
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:45834326-45862779 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 23.87 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    893 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920924
protein coding gene Chr1:45834313-45862798 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015994
protein coding gene Chr1:44870042-44899266 (+)
A/J MGP_AJ_G0015978
protein coding gene Chr1:43477621-43506137 (+)
AKR/J MGP_AKRJ_G0015933
protein coding gene Chr1:44106055-44136389 (+)
BALB/cJ MGP_BALBcJ_G0015932
protein coding gene Chr1:43099399-43127822 (+)
C3H/HeJ MGP_C3HHeJ_G0015765
protein coding gene Chr1:44523727-44552185 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016385
protein coding gene Chr1:46750363-46779948 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014107
protein coding gene Chr1:40155400-40183690 (+)
CAST/EiJ MGP_CASTEiJ_G0015346
protein coding gene Chr1:44406308-44438482 (+)
CBA/J MGP_CBAJ_G0015737
protein coding gene Chr1:48075200-48104596 (+)
DBA/2J MGP_DBA2J_G0015838
protein coding gene Chr1:42754457-42783873 (+)
FVB/NJ MGP_FVBNJ_G0015840
protein coding gene Chr1:42207816-42237167 (+)
LP/J MGP_LPJ_G0015908
protein coding gene Chr1:45172611-45201112 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015860
protein coding gene Chr1:50193845-50227296 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016432
protein coding gene Chr1:44306043-44337497 (+)
PWK/PhJ MGP_PWKPhJ_G0015129
protein coding gene Chr1:42557310-42586218 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014911
protein coding gene Chr1:44320006-44351094 (+)
WSB/EiJ MGP_WSBEiJ_G0015408
protein coding gene Chr1:44293102-44321884 (+)



Homology
more
  • Human Ortholog
    WDR75, WD repeat domain 75
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR75, WD repeat domain 75
  • Synonyms
    NET16, UTP17
  • Links
    NCBI Gene ID: 84128
    neXtProt AC: NX_Q8IWA0
    UniProt: Q8IWA0

  • Chr Location
    2q32.2; chr2:189441446-189475552 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025995 Ensembl Gene Model | MGI Sequence Detail 28454 C57BL/6J ±  kb
transcript ENSMUST00000027139 Ensembl | MGI Sequence Detail 2953 Not Applicable  
polypeptide ENSMUSP00000027139 Ensembl | MGI Sequence Detail 830 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 190
    cDNA 190

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921401, MGI:2138661
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:19723 Nishiguchi S, et al., A survey of genes expressed in undifferentiated mouse embryonal carcinoma F9 cells: characterization of low-abundance mRNAs. J Biochem. 1994 Jul;116(1):128-39
  • Latest
    J:189611 Vrljicak P, et al., Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse. PLoS One. 2012;7(7):e40815

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory