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Ccdc74a Gene Detail
Summary
  • Symbol
    Ccdc74a
  • Name
    coiled-coil domain containing 74A
  • Synonyms
    2310015A05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919565
    NCBI Gene: 72315
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:17464340-17468602 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 10.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919565
 protein coding gene Chr16:17464334-17468602 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022588
 protein coding gene Chr16:14817150-14821418 (+)
A/J MGP_AJ_G0022549
 protein coding gene Chr16:14080617-14084885 (+)
AKR/J MGP_AKRJ_G0022526
 protein coding gene Chr16:14625603-14629871 (+)
BALB/cJ MGP_BALBcJ_G0022552
 protein coding gene Chr16:14234956-14239224 (+)
C3H/HeJ MGP_C3HHeJ_G0022319
 protein coding gene Chr16:14777034-14781302 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023003
 protein coding gene Chr16:15046960-15052396 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020523
 protein coding gene Chr16:14134270-14138580 (+)
CAST/EiJ MGP_CASTEiJ_G0021847
 protein coding gene Chr16:14683262-14687600 (+)
CBA/J MGP_CBAJ_G0022290
 protein coding gene Chr16:15719328-15723596 (+)
DBA/2J MGP_DBA2J_G0022420
 protein coding gene Chr16:13995028-13999296 (+)
FVB/NJ MGP_FVBNJ_G0022396
 protein coding gene Chr16:14035677-14039945 (+)
LP/J MGP_LPJ_G0022487
 protein coding gene Chr16:14570541-14574809 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022417
 protein coding gene Chr16:15409996-15414264 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023014
 protein coding gene Chr16:14573967-14578235 (+)
PWK/PhJ MGP_PWKPhJ_G0021590
 protein coding gene Chr16:14251298-14255645 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021418
 protein coding gene Chr16:14545510-14549869 (+)
WSB/EiJ MGP_WSBEiJ_G0021894
 protein coding gene Chr16:14562000-14566270 (+)



Homology
more
  • Human Ortholog
    CCDC74A, coiled-coil domain containing 74A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC74A, coiled-coil domain containing 74A
  • Links
    NCBI Gene ID: 90557
    neXtProt AC: NX_Q96AQ1
    UniProt: Q96AQ1

  • Chr Location
    2q21.1; chr2:131522592-131533666 (+)  GRCh38
  • Human Ortholog
    CCDC74B, coiled-coil domain containing 74B
  • Links
    NCBI Gene ID: 91409
    neXtProt AC: NX_Q96LY2
    UniProt: Q96LY2

  • Chr Location
    2q21.1; chr2:130139287-130145134 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72315 NCBI Gene Model | MGI Sequence Detail 4263 C57BL/6J ±  kb
transcript NM_001166164 RefSeq | MGI Sequence Detail 1252 C57BL/6  
polypeptide NP_001159636 RefSeq | MGI Sequence Detail 364 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR039496 CCDC92/74, N-terminal
    IPR040370 Coiled-coil domain-containing protein 74A/74B/92
    IPR029422 Coiled coil protein 74, C-terminal
  • GlyGen
    E9Q9U8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Diseases 1
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:336143 Tabata H, et al., Histological Analysis of a Mouse Model of the 22q11.2 Microdeletion Syndrome. Biomolecules. 2023 Apr 27;13(5)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory