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Asb12 Gene Detail
Summary
  • Symbol
    Asb12
  • Name
    ankyrin repeat and SOCS box-containing 12
  • Synonyms
    2310036C05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917642
    NCBI Gene: 70392
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:94513807-94601593 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 41.99 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2049 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917642
 protein coding gene ChrX:94513125-94601610 (-)
129S1/SvImJ ENSMUSG00200037487
 protein coding gene ChrX:76206349-76294175 (-)
A/J ENSMUSG00195031393
 protein coding gene ChrX:79999662-80087509 (-)
AKR/J ENSMUSG00220026905
 protein coding gene ChrX:74724555-74812397 (-)
BALB/cJ ENSMUSG00180021363
 protein coding gene ChrX:76663393-76751227 (-)
C3H/HeJ ENSMUSG00175018595
 protein coding gene ChrX:80358430-80446254 (-)
C57BL/6NJ ENSMUSG00215016773
 protein coding gene ChrX:76882600-76970432 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033245
 protein coding gene ChrX:90089512-90097136 (-)
CAST/EiJ ENSTCUG00005026963
 protein coding gene ChrX:77873617-77970861 (-)
CBA/J ENSMUSG00210033302
 protein coding gene ChrX:77098337-77186162 (-)
DBA/2J ENSMUSG00185030522
 protein coding gene ChrX:89574842-89662685 (-)
FVB/NJ ENSMUSG00205022788
 protein coding gene ChrX:76345494-76433398 (-)
JF1/MsJ ENSUMUG00000019465
 protein coding gene ChrX:110209717-110309557 (-)
LP/J ENSMUSG00230011429
 protein coding gene ChrX:96269497-96357328 (-)
NOD/ShiLtJ ENSMUSG00190017079
 protein coding gene ChrX:76242956-76330780 (-)
NZO/HlLtJ ENSMUSG00225045362
 protein coding gene ChrX:101400427-101488339 (-)
PWK/PhJ ENSLUMG00010034956
 protein coding gene ChrX:75513133-75619480 (-)
SPRET/EiJ ENSMSPG00010031700
 protein coding gene ChrX:79630451-79663065 (-)
WSB/EiJ ENSIUOG00005040381
 protein coding gene ChrX:76877710-76979584 (-)



Homology
more
  • Human Ortholog
    ASB12, ankyrin repeat and SOCS box containing 12
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASB12, ankyrin repeat and SOCS box containing 12
  • Links
    NCBI Gene ID: 142689
    UniProt: Q8WXK4

  • Chr Location
    Xq11.2; chrX:64224194-64230607 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mice homologous for a null allele exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031204 Ensembl Gene Model | MGI Sequence Detail 87787 C57BL/6J ±  kb
transcript ENSMUST00000033549 Ensembl | MGI Sequence Detail 1258 Not Applicable  
polypeptide ENSMUSP00000033549 Ensembl | MGI Sequence Detail 308 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:324158 Zhang R, et al., Testis-enriched Asb12 is not required for spermatogenesis and fertility in mice. Transl Androl Urol. 2022 Feb;11(2):168-178
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory