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Gprc5c Gene Detail
Summary
  • Symbol
    Gprc5c
  • Name
    G protein-coupled receptor, family C, group 5, member C
  • Synonyms
    1110028I06Rik, 3200002M13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917605
    NCBI Gene: 70355
  • Alliance
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:114741978-114763443 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.54 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    686 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917605
protein coding gene Chr11:114741976-114763443 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019362
protein coding gene Chr11:118803307-118824683 (+)
A/J MGP_AJ_G0019331
protein coding gene Chr11:113635022-113659612 (+)
AKR/J MGP_AKRJ_G0019299
protein coding gene Chr11:116997235-117016557 (+)
BALB/cJ MGP_BALBcJ_G0019304
protein coding gene Chr11:114050290-114069240 (+)
C3H/HeJ MGP_C3HHeJ_G0019113
protein coding gene Chr11:117346811-117372513 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019755
protein coding gene Chr11:122370698-122391216 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017378
protein coding gene Chr11:110696949-110716624 (+)
CAST/EiJ MGP_CASTEiJ_G0018667
protein coding gene Chr11:118680835-118704463 (+)
CBA/J MGP_CBAJ_G0019083
protein coding gene Chr11:127269945-127294871 (+)
DBA/2J MGP_DBA2J_G0019195
protein coding gene Chr11:113073099-113092685 (+)
FVB/NJ MGP_FVBNJ_G0019186
protein coding gene Chr11:112558470-112580164 (+)
LP/J MGP_LPJ_G0019265
protein coding gene Chr11:119208082-119232495 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019217
protein coding gene Chr11:126414767-126436362 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019792
protein coding gene Chr11:117674179-117694244 (+)
PWK/PhJ MGP_PWKPhJ_G0018432
protein coding gene Chr11:114310723-114332860 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018224
protein coding gene Chr11:117478465-117500071 (+)
WSB/EiJ MGP_WSBEiJ_G0018719
protein coding gene Chr11:117633310-117654510 (+)



Homology
more
  • Human Ortholog
    GPRC5C, G protein-coupled receptor class C group 5 member C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPRC5C, G protein-coupled receptor class C group 5 member C
  • Synonyms
    RAIG-3, RAIG3
  • Links
    NCBI Gene ID: 55890
    neXtProt AC: NX_Q9NQ84
    UniProt: Q9NQ84

  • Chr Location
    17q25.1; chr17:74424851-74451658 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a reporter allele are behaviorally normal but exhibit reticulocytosis, increased mean corpuscular volume, increased percentage of basophils, decreased mean corpuscular hemogloblin concentration, and increased alkaline phophatase and lactic dehydrogenase levels.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051043 Ensembl Gene Model | MGI Sequence Detail 21466 C57BL/6J ±  kb
    transcript ENSMUST00000053361 Ensembl | MGI Sequence Detail 3667 Not Applicable  
    polypeptide ENSMUSP00000061760 Ensembl | MGI Sequence Detail 441 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 66
      cDNA 63
      Primer pair 1
      Other 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1915929
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 6
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    10/22/2024
    MGI 6.24
    The Jackson Laboratory