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Washc3 Gene Detail
Summary
  • Symbol
    Washc3
  • Name
    WASH complex subunit 3
  • Synonyms
    2900091E11Rik, 5730495F03Rik, Ccdc53
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914532
    NCBI Gene: 67282
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:88036955-88082020 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 43.70 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1392 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914532
 protein coding gene Chr10:88036954-88160001 (+)
129S1/SvImJ ENSMUSG00200028133
 protein coding gene Chr10:84534885-84579949 (+)
A/J ENSMUSG00195021539
 protein coding gene Chr10:84979423-85024318 (+)
AKR/J ENSMUSG00220021117
 protein coding gene Chr10:84585957-84630851 (+)
BALB/cJ ENSMUSG00180030408
 protein coding gene Chr10:84982485-85027378 (+)
C3H/HeJ ENSMUSG00175021024
 protein coding gene Chr10:84872927-84917820 (+)
C57BL/6NJ ENSMUSG00215014683
 protein coding gene Chr10:84537495-84582564 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015705
 protein coding gene Chr10:82021166-82069612 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210031145
 protein coding gene Chr10:84713371-84758265 (+)
DBA/2J ENSMUSG00185038389
 protein coding gene Chr10:84939073-84984046 (+)
FVB/NJ ENSMUSG00205014250
 protein coding gene Chr10:84560179-84605489 (+)
JF1/MsJ ENSUMUG00000013173
 protein coding gene Chr10:86268898-86313678 (+)
LP/J ENSMUSG00230015749
 protein coding gene Chr10:86817431-86862313 (+)
NOD/ShiLtJ ENSMUSG00190015962
 protein coding gene Chr10:84964705-85009597 (+)
NZO/HlLtJ ENSMUSG00225048364
 protein coding gene Chr10:91088021-91132913 (+)
PWK/PhJ ENSLUMG00010022856
 protein coding gene Chr10:84560637-84605932 (+)
SPRET/EiJ ENSMSPG00010032082
 protein coding gene Chr10:86055245-86103407 (+)
WSB/EiJ ENSIUOG00005036402
 protein coding gene Chr10:84644171-84689186 (+)



Homology
more
  • Human Ortholog
    WASHC3, WASH complex subunit 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WASHC3, WASH complex subunit 3
  • Synonyms
    CCDC53, CGI-116
  • Links
    NCBI Gene ID: 51019
    UniProt: Q9Y3C0

  • Chr Location
    12q23.2; chr12:102011769-102062149 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    10
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    652
  • Tissues
    38
  • cDNA Data
    84
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020056 Ensembl Gene Model | MGI Sequence Detail 45066 C57BL/6J ±  kb
    transcript ENSMUST00000020248 Ensembl | MGI Sequence Detail 1052 Not Applicable  
    polypeptide ENSMUSP00000020248 Ensembl | MGI Sequence Detail 194 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 84
      cDNA 84

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1917877
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory