Gene Expression Data
Assay Details
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Assay
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Reference:
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J:55705
Nardelli J, et al., Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Dev Biol. 1999 Jun 15;210(2):305-21
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1342723
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Gene symbol:
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Gata3
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Gene name:
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GATA binding protein 3
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Probe:
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GATA-3 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
1.B:
embryonic day 9.0
(more  )
Specimen
1.B:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1.D:
embryonic day 9.5
(more )
Specimen
1.D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1.F:
embryonic day 10.5
(more )
Specimen
1.F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: telencephalon |
Present |
Regionally restricted |
1F
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Expression is detected in the olfactory bulb.
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| TS17: midbrain roof plate |
Present |
Regionally restricted |
1F
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Expression is detected in the pretectum.
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| TS17: central nervous system ganglion |
Present |
Regionally restricted |
1F
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Expression is detected in the common oculomotor nucleus.
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| TS17: future spinal cord |
Present |
Regionally restricted |
1F
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Expression is detected in a ventrolateral column spanning the hindbrain and the spinal cord; ventral extension of expression is seen only in r4.
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| TS17: hindbrain |
Present |
Regionally restricted |
1F
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Expression is detected in a ventrolateral column spanning the hindbrain and the spinal cord; ventral extension of expression is seen only in r4.
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Specimen
1.H:
embryonic day 11.5
(more )
Specimen
1.H:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2.D:
embryonic day 9.5
(more )
Specimen
2.D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2.E:
embryonic day 10.5
(more )
Specimen
2.E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Present |
Regionally restricted |
2E
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Expression is detected in a narrow column of cells lining the floor plate and a more lateral column, which abuts the former domain from rostral hindbrain to r4. Expression is fainter than that of Gata2 close to the floor plate from the r1/r2 boundary.
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Specimen
2.F:
embryonic day 11.5
(more )
Specimen
2.F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: hindbrain |
Present |
Regionally restricted |
2F
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Expression is detected ventrally downward from the mesencephalon; it is downregulated in r2.
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Specimen
3.F:
embryonic day 10.5
(more )
Specimen
3.F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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section from whole mount
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Specimen
3.G:
embryonic day 10.5
(more )
Specimen
3.G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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section from whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: rhombomere 1 |
Present |
Regionally restricted |
3G
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Expression is detected throughout the mediolateral axis of the ventral neural tube in r1, with a marked activation in a cluster of cells which juxtapose the floor plate.
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Specimen
3.H:
embryonic day 10.5
(more )
Specimen
3.H:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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section from whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: rhombomere 4 |
Strong |
Regionally restricted |
3H
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Expression is very strongly activated laterally in ventral r4, but expression gradually declines toward the ventricular zone.
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Specimen
3.I:
embryonic day 10.5
(more )
Specimen
3.I:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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section from whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: rhombomere 6 |
Trace |
Regionally restricted |
3I
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In r6 expression is barely detectable close to the floor plate and in the ventricular zone.
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Specimen
3.J:
embryonic day 10.5
(more )
Specimen
3.J:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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section from whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: future spinal cord |
Present |
Regionally restricted |
3J
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Expression is restricted to the subventricular zone.
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Specimen
4.A:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Gata2tm1Sho/Gata2tm1Sho
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4.B:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Gata2tm1Sho/Gata2tm1Sho
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
not shown:
embryonic day 8.5
(more )
Specimen
not shown:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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