About   Help   FAQ
Gsta1 Gene Detail
Summary
  • Symbol
    Gsta1
  • Name
    glutathione S-transferase, alpha 1 (Ya)
  • Synonyms
    Gst2-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1095417
    NCBI Gene: 14857
  • Member of
    Gsta cluster
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:78137951-78149965 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 43.65 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    209 from dbSNP Build 142
  • Strain Annotations
    11
  • RFLP
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1095417
 protein coding gene Chr9:78137938-78149966 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035063
 protein coding gene Chr9:78747649-78762143 (+)
A/J MGP_AJ_G0035046
 protein coding gene Chr9:76099935-76117373 (-)
AKR/J MGP_AKRJ_G0034971
 protein coding gene Chr9:77816252-77825449 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0034742
 protein coding gene Chr9:78285685-78374341 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035551
 protein coding gene Chr9:80810359-80837318 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0034716
 protein coding gene Chr9:83657741-83721221 (+)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0034820
 protein coding gene Chr9:74969720-74986597 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0034859
 protein coding gene Chr9:84813826-84837355 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035579
 protein coding gene Chr9:78061367-78088584 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0034178
 protein coding gene Chr9:77890173-77896041 (+)



Homology
more
  • Human Ortholog
    GSTA1, glutathione S-transferase alpha 1
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GSTA1, glutathione S-transferase alpha 1
  • Synonyms
    GST2, GSTA1-1, GST-epsilon, GTH1
  • Links
    NCBI Gene ID: 2938
    neXtProt AC: NX_P08263
    UniProt: P08263

  • Chr Location
    6p12.2; chr6:52791371-52803860 (-)  GRCh38
  • Human Ortholog
    GSTA2, glutathione S-transferase alpha 2
  • Synonyms
    GST2, GSTA2-2, GTA2, GTH2
  • Links
    NCBI Gene ID: 2939
    neXtProt AC: NX_P09210
    UniProt: P09210

  • Chr Location
    6p12.2; chr6:52750087-52763475 (-)  GRCh38
  • Human Ortholog
    GSTA3, glutathione S-transferase alpha 3
  • Synonyms
    GSTA3-3, GTA3
  • Links
    NCBI Gene ID: 2940
    neXtProt AC: NX_Q16772
    UniProt: Q16772

  • Chr Location
    6p12.2; chr6:52896639-52909698 (-)  GRCh38
  • Human Ortholog
    GSTA5, glutathione S-transferase alpha 5
  • Links
    NCBI Gene ID: 221357
    neXtProt AC: NX_Q7RTV2
    UniProt: Q7RTV2

  • Chr Location
    6p12.2; chr6:52831655-52846245 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human GSTA1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    915
  • Tissues
    153
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14857 NCBI Gene Model | MGI Sequence Detail 12015 C57BL/6J ±  kb
transcript NM_008181 RefSeq | MGI Sequence Detail 861 ZRU/MplStud  
polypeptide P13745 UniProt | EBI | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 24
    Genomic 5
    cDNA 17
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-10308, MGI:3801841, MGI:95854
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Gene Ontology 12
    Phenotypes 9
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:334703 Habeos GI, et al., Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2. Antioxidants (Basel). 2022 Nov 17;11(11)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory