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Zfp185 Gene Detail
Summary
  • Symbol
    Zfp185
  • Name
    zinc finger protein 185
  • Synonyms
    P1-
  • Feature Type
    protein coding gene
  • IDs
    MGI:108095
    NCBI Gene: 22673
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:72030945-72075149 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 37.29 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    515 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108095
 protein coding gene ChrX:72030860-72075149 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035797
 protein coding gene ChrX:68683928-68728731 (+)
A/J MGP_AJ_G0035781
 protein coding gene ChrX:68877720-68922611 (+)
AKR/J MGP_AKRJ_G0035703
 protein coding gene ChrX:70722062-70766588 (+)
BALB/cJ MGP_BALBcJ_G0035768
 protein coding gene ChrX:67898603-67943529 (+)
C3H/HeJ MGP_C3HHeJ_G0035471
 protein coding gene ChrX:69178492-69225461 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036298
 protein coding gene ChrX:70762011-70808290 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033145
 protein coding gene ChrX:67999243-68042130 (+)
CAST/EiJ MGP_CASTEiJ_G0034763
 protein coding gene ChrX:54493877-54538735 (+)
CBA/J MGP_CBAJ_G0035446
 protein coding gene ChrX:72685821-72737096 (+)
DBA/2J MGP_DBA2J_G0035599
 protein coding gene ChrX:68370548-68415571 (+)
FVB/NJ MGP_FVBNJ_G0035550
 protein coding gene ChrX:67706797-67752103 (+)
LP/J MGP_LPJ_G0035688
 protein coding gene ChrX:69536543-69580747 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035585
 protein coding gene ChrX:75313557-75360591 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036319
 protein coding gene ChrX:68528823-68573784 (+)
PWK/PhJ MGP_PWKPhJ_G0034463
 protein coding gene ChrX:52492763-52538283 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034298
 protein coding gene ChrX:55441789-55487143 (+)
WSB/EiJ MGP_WSBEiJ_G0034905
 protein coding gene ChrX:67826239-67870674 (+)



Homology
more
  • Human Ortholog
    ZNF185, zinc finger protein 185 with LIM domain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF185, zinc finger protein 185 with LIM domain
  • Synonyms
    SCELL
  • Links
    NCBI Gene ID: 7739
    UniProt: O15231

  • Chr Location
    Xq28; chrX:152898067-152973481 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a null allele display increased vascular permeability under inflammatory conditions.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    884
  • Tissues
    72
  • cDNA Data
    29
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031351 Ensembl Gene Model | MGI Sequence Detail 44205 C57BL/6J ±  kb
    transcript ENSMUST00000164800 Ensembl | MGI Sequence Detail 3557 Not Applicable  
    polypeptide ENSMUSP00000126066 Ensembl | MGI Sequence Detail 486 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 29
      Primer pair 5

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-37132
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 10
      Phenotypes 6
    • Earliest
      J:33576 Levin ML, et al., A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77
    • Latest
      J:345303 Suzuki S, et al., ZNF185 prevents stress fiber formation through the inhibition of RhoA in endothelial cells. Commun Biol. 2023 Jan 11;6(1):29
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory