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Sebox Gene Detail
Summary
  • Symbol
    Sebox
  • Name
    SEBOX homeobox
  • Synonyms
    OG9, Og9x
  • Feature Type
    protein coding gene
  • IDs
    MGI:108012
    NCBI Gene: 18292
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78394328-78395907 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108012
 protein coding gene Chr11:78394273-78395907 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018783
 protein coding gene Chr11:79523419-79525053 (+)
A/J MGP_AJ_G0018749
 protein coding gene Chr11:76474535-76476169 (+)
AKR/J MGP_AKRJ_G0018719
 protein coding gene Chr11:78778197-78779831 (+)
BALB/cJ MGP_BALBcJ_G0018723
 protein coding gene Chr11:76877645-76879279 (+)
C3H/HeJ MGP_C3HHeJ_G0018536
 protein coding gene Chr11:78825143-78826777 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019174
 protein coding gene Chr11:81990720-81992354 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016809
 protein coding gene Chr11:73444693-73446302 (+)
CAST/EiJ MGP_CASTEiJ_G0018090
 protein coding gene Chr11:79281875-79283504 (+)
CBA/J MGP_CBAJ_G0018507
 protein coding gene Chr11:85600717-85602351 (+)
DBA/2J MGP_DBA2J_G0018615
 protein coding gene Chr11:76049214-76050848 (+)
FVB/NJ MGP_FVBNJ_G0018605
 protein coding gene Chr11:75639708-75641342 (+)
LP/J MGP_LPJ_G0018686
 protein coding gene Chr11:80036819-80038453 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018631
 protein coding gene Chr11:85961937-85963571 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019214
 protein coding gene Chr11:79027012-79028646 (+)
PWK/PhJ MGP_PWKPhJ_G0017861
 protein coding gene Chr11:76845635-76847267 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017652
 protein coding gene Chr11:78642651-78644282 (+)
WSB/EiJ MGP_WSBEiJ_G0018143
 protein coding gene Chr11:78856348-78857982 (+)



Homology
more
  • Human Ortholog
    SEBOX, SEBOX homeobox
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SEBOX, SEBOX homeobox
  • Synonyms
    OG-9, OG9, OG9X
  • Links
    NCBI Gene ID: 645832
    UniProt: Q9HB31

  • Chr Location
    17q11.2; chr17:28363506-28365199 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Adult mice homozygous for a targeted disruption of this gene display normal retinal morphology as well as normal electroretinograms under scotopic and photopic conditions.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    942
  • Tissues
    143
  • cDNA Data
    17
  • Literature Summary
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 18292 NCBI Gene Model | MGI Sequence Detail 1580 C57BL/6J ±  kb
transcript NM_008759 RefSeq | MGI Sequence Detail 1296 ZRU/MplStud  
polypeptide P70368 UniProt | EBI | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 1
    cDNA 17
    Primer pair 5
    Other 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-37046
References
more
  • Summaries
    All 47
    Developmental Gene Expression 12
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory