Tex2 MGI Mouse Gene Detail - MGI:102465

Symbol

Tex2
Name

testis expressed gene 2
Synonyms

4930568E07Rik, Def-5, mKIAA1738, Taz4

Feature Type

protein coding gene
IDs

MGI:102465
NCBI Gene: 21763
Alliance

gene page
Transcription Start Sites

18 TSS

Sequence Map

Chr11:106392973-106504249 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 69.46 cM, cytoband D
Mapping Data

6 experiments

SNPs within 2kb

3217 from dbSNP Build 142
Strain Annotations

18
RFLP

2

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_102465	protein coding gene	Chr11:106392965-106504259 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019309	protein coding gene	Chr11:109801806-109925761 (-)
A/J	MGP_AJ_G0019277	protein coding gene	Chr11:105128693-105240537 (-)
AKR/J	MGP_AKRJ_G0019246	protein coding gene	Chr11:108259585-108377390 (-)
BALB/cJ	MGP_BALBcJ_G0019251	protein coding gene	Chr11:105537932-105651554 (-)
C3H/HeJ	MGP_C3HHeJ_G0019060	protein coding gene	Chr11:108553783-108670758 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0019701	protein coding gene	Chr11:113175866-113302086 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017325	protein coding gene	Chr11:102405533-102515027 (-)
CAST/EiJ	MGP_CASTEiJ_G0018613	protein coding gene	Chr11:109628468-109744305 (-)
CBA/J	MGP_CBAJ_G0019029	protein coding gene	Chr11:117874932-118006546 (-)
DBA/2J	MGP_DBA2J_G0019141	protein coding gene	Chr11:104598372-104710697 (-)
FVB/NJ	MGP_FVBNJ_G0019132	protein coding gene	Chr11:104106410-104220683 (-)
LP/J	MGP_LPJ_G0019211	protein coding gene	Chr11:110241041-110368772 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019162	protein coding gene	Chr11:117142247-117259146 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019738	protein coding gene	Chr11:108752241-108873417 (-)
PWK/PhJ	MGP_PWKPhJ_G0018378	protein coding gene	Chr11:105694315-105811523 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0018169	protein coding gene	Chr11:108532994-108658550 (-)
WSB/EiJ	MGP_WSBEiJ_G0018664	protein coding gene	Chr11:108732808-108852501 (-)

Human Ortholog

TEX2, testis expressed 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TEX2, testis expressed 2
Synonyms

HT008, TMEM96
Links

HGNC:30884

NCBI Gene ID: 55852

UniProt: Q8IWB9
Chr Location

17q23.3; chr17:64147227-64263260 (-) GRCh38

MGI Vertebrate Homology

Tex2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TEX2
Gene Tree

Tex2

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Phenotype Summary

18 phenotypes from 2 alleles in 2 genetic backgrounds
15 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

116
Endonuclease-mediated

5
Gene trapped

109
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

160 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

886
Tissues

65
cDNA Data

11
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tex2, tex2.2

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All Sequences

76
RefSeq

20
UniProt

7
CCDS

CCDS25557.1

Ensembl

ENSMUSG00000040548 (Evidence)
NCBI Gene

21763

			Length	Strain/Species	Flank
genomic	ENSMUSG00000040548	Ensembl Gene Model \| MGI Sequence Detail	111277	C57BL/6J	± kb
transcript	ENSMUST00000042780	Ensembl \| MGI Sequence Detail	4934	Not Applicable
polypeptide	ENSMUSP00000041985	Ensembl \| MGI Sequence Detail	1128	Not Applicable

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UniProt

7 Sequences
Protein Ontology

PR:000016256 testis-expressed protein 2

(term hierarchy)
InterPro Domains

IPR031468 Synaptotagmin-like mitochondrial-lipid-binding domain
GlyGen

Q6ZPJ0 5 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (2 sites)

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All nucleic 13

Genomic 1

cDNA 12

Microarray probesets 6

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MGD-MRK-19302, MGI:1915001, MGI:2144222

Summaries

All 43

Developmental Gene Expression 2

Gene Ontology 1

Phenotypes 15
Earliest

J:18471 Lemaire L, et al., Chromosomal assignment of three novel mouse genes expressed in testicular cells. Genomics. 1994 May 15;21(2):409-14
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Tex2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr111372	Chr11:106504196-106504210 (-)	46 bp
Tssr111371	Chr11:106503879-106503890 (-)	364 bp
Tssr111370	Chr11:106503858-106503878 (-)	381 bp
Tssr111369	Chr11:106503839-106503850 (-)	404 bp
Tssr111368	Chr11:106503817-106503833 (-)	424 bp
Tssr111367	Chr11:106503754-106503799 (-)	472 bp
Tssr111366	Chr11:106479696-106479707 (-)	24,547 bp
Tssr111365	Chr11:106478763-106478774 (-)	25,480 bp
Tssr111364	Chr11:106471420-106471435 (-)	32,821 bp
Tssr111363	Chr11:106469937-106469967 (-)	34,297 bp
Tssr111362	Chr11:106469919-106469931 (-)	34,324 bp
Tssr111361	Chr11:106469900-106469913 (-)	34,342 bp
Tssr111360	Chr11:106463008-106463026 (-)	41,232 bp
Tssr111359	Chr11:106459245-106459259 (-)	44,997 bp
Tssr111358	Chr11:106420923-106420947 (-)	83,314 bp
Tssr111357	Chr11:106405063-106405067 (-)	99,184 bp
Tssr111356	Chr11:106397894-106397932 (-)	106,336 bp
Tssr111355	Chr11:106394125-106394129 (-)	110,122 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24