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Iglv2 Gene Detail
Summary
  • Symbol
    Iglv2
  • Name
    immunoglobulin lambda variable 2
  • Feature Type
    gene segment
  • IDs
    MGI:99548
    NCBI Gene: 110612
  • Alliance
  • Transcription Start Sites
    1 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr16:19079153-19079594 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 11.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    16
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99548
gene segment Chr16:19079151-19079609 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000106
gene segment Chr16:16537374-16539068 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0000106
gene segment Chr16:16357062-16357520 (-)
BALB/cJ MGP_BALBcJ_G0000093
gene segment Chr16:15891683-15892141 (-)
C3H/HeJ MGP_C3HHeJ_G0000102
gene segment Chr16:16520480-16520938 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000142
gene segment Chr16:16855446-16856258 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0000109
gene segment Chr16:16257828-16258389 (-)
CBA/J MGP_CBAJ_G0000100
gene segment Chr16:17581439-17581897 (-)
DBA/2J MGP_DBA2J_G0000095
gene segment Chr16:15621617-15622075 (-)
FVB/NJ MGP_FVBNJ_G0000095
gene segment Chr16:15707099-15707557 (-)
LP/J MGP_LPJ_G0000112
gene segment Chr16:16288475-16289289 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0000110
gene segment Chr16:17200679-17201137 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000127
gene segment Chr16:16271985-16272775 (-)
PWK/PhJ MGP_PWKPhJ_G0000097
gene segment Chr16:15943100-15943622 (-)
SPRET/EiJ MGP_SPRETEiJ_G0000073
gene segment Chr16:16272427-16272886 (+)
WSB/EiJ MGP_WSBEiJ_G0000107
gene segment Chr16:16317456-16317914 (-)



Homology
more
  • Human Ortholog
    IGLV7-43, immunoglobulin lambda variable 7-43
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGLV7-43, immunoglobulin lambda variable 7-43
  • Synonyms
    IGLV743, V3-2
  • Links
    NCBI Gene ID: 28776
    UniProt: P04211

  • Chr Location
    22q11.22; chr22:22395018-22395489 (+)  GRCh38

  • Human Ortholog
    IGLV7-46, immunoglobulin lambda variable 7-46
  • Synonyms
    IGLV746, V3-3
  • Links
    NCBI Gene ID: 28775
    UniProt: A0A075B6I9

  • Chr Location
    22q11.22; chr22:22369614-22370087 (+)  GRCh38

  • Human Ortholog
    IGLV8-61, immunoglobulin lambda variable 8-61
  • Synonyms
    IGLV861, V3-4
  • Links
    NCBI Gene ID: 28774
    UniProt: A0A075B6I0

  • Chr Location
    22q11.22; chr22:22098700-22099212 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 110612 NCBI Gene Model | MGI Sequence Detail 442 C57BL/6J ±  kb
transcript BC106995 GenBank | ENA | DDBJ | MGI Sequence Detail 715 Not Specified  
polypeptide P01728 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR003599 Immunoglobulin subtype
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 14
    Genomic 9
    cDNA 5

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-16326
References
more
  • Summaries
    All 18
  • Earliest
    J:32610 Tonegawa S, et al., Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. Proc Natl Acad Sci U S A. 1978 Mar;75(3):1485-9
  • Latest
    J:152405 Kurey I, et al., Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics. 2009 Sep;61(9):619-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory