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Rab11b Gene Detail
Summary
  • Symbol
    Rab11b
  • Name
    RAB11B, member RAS oncogene family
  • Synonyms
    A730055L17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:99425
    NCBI Gene: 19326
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:33961458-33979460 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99425
 protein coding gene Chr17:33961458-33979504 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023535
 protein coding gene Chr17:33672312-33691266 (-)
A/J MGP_AJ_G0023494
 protein coding gene Chr17:32517582-32536237 (-)
AKR/J MGP_AKRJ_G0023460
 protein coding gene Chr17:32894522-32911661 (-)
BALB/cJ MGP_BALBcJ_G0023498
 protein coding gene Chr17:32663933-32683215 (-)
C3H/HeJ MGP_C3HHeJ_G0023261
 protein coding gene Chr17:33232917-33251822 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023942
 protein coding gene Chr17:34915069-34938160 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021415
 protein coding gene Chr17:30033127-30046326 (-)
CAST/EiJ MGP_CASTEiJ_G0022763
 protein coding gene Chr17:33354071-33374484 (-)
CBA/J MGP_CBAJ_G0023237
 protein coding gene Chr17:36312636-36335853 (-)
DBA/2J MGP_DBA2J_G0023366
 protein coding gene Chr17:31898948-31917203 (-)
FVB/NJ MGP_FVBNJ_G0023335
 protein coding gene Chr17:31759894-31775172 (-)
LP/J MGP_LPJ_G0023444
 protein coding gene Chr17:33950950-33970153 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023355
 protein coding gene Chr17:35361685-35385927 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023982
 protein coding gene Chr17:33218406-33238858 (-)
PWK/PhJ MGP_PWKPhJ_G0022511
 protein coding gene Chr17:30790141-30807759 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022327
 protein coding gene Chr17:31193243-31211756 (-)
WSB/EiJ MGP_WSBEiJ_G0022822
 protein coding gene Chr17:33261199-33281457 (-)



Homology
more
  • Human Ortholog
    RAB11B, RAB11B, member RAS oncogene family
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB11B, RAB11B, member RAS oncogene family
  • Synonyms
    H-YPT3, NDAGSCW
  • Links
    NCBI Gene ID: 9230
    neXtProt AC: NX_Q15907
    UniProt: Q15907

  • Chr Location
    19p13.2; chr19:8389981-8404434 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    52
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    13
  • cDNA Data
    197
  • Literature Summary
    16
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19326 NCBI Gene Model | MGI Sequence Detail 18003 C57BL/6J ±  kb
transcript NM_008997 RefSeq | MGI Sequence Detail 6065 ZRU/MplStud  
polypeptide P46638 UniProt | EBI | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 203
    Genomic 4
    cDNA 197
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-16188, MGI:2444458
References
more
  • Summaries
    All 65
    Developmental Gene Expression 16
    Gene Ontology 15
    Phenotypes 9
  • Earliest
    J:19871 Lai F, et al., Molecular analysis of mouse Rab11b: a new type of mammalian YPT/Rab protein. Genomics. 1994 Aug;22(3):610-6
  • Latest
    J:342449 Joseph I, et al., RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells. EMBO Rep. 2023 Sep 6;24(9):e56240
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory