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Dynlt1b Gene Detail
Summary
  • Symbol
    Dynlt1b
  • Name
    dynein light chain Tctex-type 1B
  • Synonyms
    Dynlt1, Tctex1, Tctex-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98643
    NCBI Gene: 21648
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:6697511-6703695 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 3.97 cM
  • Mapping Data
    11 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7 from dbSNP Build 142
  • Strain Annotations
    6
  • RFLP
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98643
 protein coding gene Chr17:6697511-6703695 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023114
 protein coding gene Chr17:3620489-3626852 (+)
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0022922
 protein coding gene Chr17:3291145-3301873 (-)
LP/J MGP_LPJ_G0023018
 protein coding gene Chr17:3624874-3638338 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0023549
 protein coding gene Chr17:3686768-3688778 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0022415
 protein coding gene Chr17:3809563-3816619 (-)



Homology
more
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Synonyms
    CW-1, TCTEL1, tctex-1, TCTEX1
  • Links
    NCBI Gene ID: 6993
    neXtProt AC: NX_P63172
    UniProt: P63172

  • Chr Location
    6q25.3; chr6:158636474-158644743 (-)  GRCh38
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    330 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    49
  • GO References
    22
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    746
  • Tissues
    32
  • cDNA Data
    15
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 21648 NCBI Gene Model | MGI Sequence Detail 6185 C57BL/6J ±  kb
transcript NM_009342 RefSeq | MGI Sequence Detail 791 ZRU/MplStud  
polypeptide P51807 UniProt | EBI | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    Genomic 1
    cDNA 20
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-14949, MGD-MRK-14963
References
more
  • Summaries
    All 387
    Developmental Gene Expression 7
    Diseases 6
    Gene Ontology 22
    Phenotypes 330
  • Earliest
    J:9988 Lader E, et al., tctex-1: a candidate gene family for a mouse t complex sterility locus. Cell. 1989 Sep 8;58(5):969-79
  • Latest
    J:346702 Colombi I, et al., Heterogeneous subpopulations of GABA(A)R-responding neurons coexist across neuronal network scales and developmental stages in health and disease. iScience. 2024 Apr 19;27(4):109438
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory