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Trbv12-1 Gene Detail
Summary
  • Symbol
    Trbv12-1
  • Name
    T cell receptor beta, variable 12-1
  • Synonyms
    Gm16753
  • Feature Type
    gene segment
  • IDs
    MGI:98602
    NCBI Gene: 100124672
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:41090501-41091001 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 19.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    22 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98602
gene segment Chr6:41090484-41091001 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002581
gene segment Chr6:39593705-39594222 (+)
A/J MGP_AJ_G0002552
gene segment Chr6:37867985-37868502 (+)
AKR/J MGP_AKRJ_G0002543
gene segment Chr6:39070618-39071135 (+)
BALB/cJ MGP_BALBcJ_G0002538
gene segment Chr6:38079990-38080507 (+)
C3H/HeJ MGP_C3HHeJ_G0002505
gene segment Chr6:39093926-39094443 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002679
gene segment Chr6:40579175-40579692 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002248
gene segment Chr6:35658042-35658658 (+)
CAST/EiJ MGP_CASTEiJ_G0002490
gene segment Chr6:38984155-38984690 (+)
CBA/J MGP_CBAJ_G0002504
gene segment Chr6:42214293-42214810 (+)
DBA/2J MGP_DBA2J_G0002508
gene segment Chr6:37681113-37681630 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0002587
gene segment Chr6:39605983-39606500 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002511
gene segment Chr6:44464807-44465324 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002689
gene segment Chr6:39046653-39047170 (+)
PWK/PhJ MGP_PWKPhJ_G0002450
gene segment Chr6:37306139-37306707 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002402
gene segment Chr6:38740160-38740659 (+)
WSB/EiJ MGP_WSBEiJ_G0002506
gene segment Chr6:38977026-38977528 (+)



Homology
more
  • Human Ortholog
    TRBV13, T cell receptor beta variable 13
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRBV13, T cell receptor beta variable 13
  • Synonyms
    TCRBV13S1, TCRBV23S1A2T
  • Links
    NCBI Gene ID: 28574
    UniProt: A0A0A6YYD4

  • Chr Location
    7q34; chr7:142535809-142536292 (+)  GRCh38

  • Human Ortholog
    TRBV5-1, T cell receptor beta variable 5-1
  • Synonyms
    TCRBV5S1, TCRBV5S1A1T, TRBV51
  • Links
    NCBI Gene ID: 28614
    UniProt: A0A578

  • Chr Location
    7q34; chr7:142320677-142321544 (+)  GRCh38

  • Human Ortholog
    TRBV5-3, T cell receptor beta variable 5-3 (non-functional)
  • Synonyms
    TCRBV5S3, TCRBV5S5P, TRBV53
  • Links
    NCBI Gene ID: 28612
    UniProt: A0A0A0MS03

  • Chr Location
    7q34; chr7:142389202-142389668 (+)  GRCh38

  • Human Ortholog
    TRBV5-8, T cell receptor beta variable 5-8
  • Synonyms
    TCRBV5S4A2T, TCRBV5S8, TRBV58
  • Links
    NCBI Gene ID: 28607
    UniProt: A0A5A2

  • Chr Location
    7q34

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 100124672 NCBI Gene Model | MGI Sequence Detail 501 C57BL/6J ±  kb
polypeptide A0A0B4J1H0 UniProt | EBI | MGI Sequence Detail 124 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 10
    Genomic 9
    Other 1
Other
Accession IDs
less
MGD-MRK-14894, MGI:4439677
References
more
  • Summaries
    All 10
    Gene Ontology 1
  • Earliest
    J:8736 Lai E, et al., Genomic organization of the mouse T-cell receptor beta-chain gene family. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3846-50
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory