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Svs4 Gene Detail
Summary
  • Symbol
    Svs4
  • Name
    seminal vesicle secretory protein 4
  • Synonyms
    Svp2, Svp-2, Svp4, Svp-4, SVS-IV
  • Feature Type
    protein coding gene
  • IDs
    MGI:98450
    NCBI Gene: 20941
  • Alliance
    gene page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164117876-164120227 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.01 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98450
 protein coding gene Chr2:164117872-164120379 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026845
 protein coding gene Chr2:169695490-169697912 (-)
A/J MGP_AJ_G0026809
 protein coding gene Chr2:162799892-162802401 (-)
AKR/J MGP_AKRJ_G0026782
 protein coding gene Chr2:167625983-167628605 (-)
BALB/cJ MGP_BALBcJ_G0026818
 protein coding gene Chr2:163139414-163142377 (-)
C3H/HeJ MGP_C3HHeJ_G0026562
 protein coding gene Chr2:167980920-167983426 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027267
 protein coding gene Chr2:174612754-174615261 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024639
 protein coding gene Chr2:156216900-156218928 (-)
CAST/EiJ MGP_CASTEiJ_G0026022
 protein coding gene Chr2:168400578-168404603 (-)
CBA/J MGP_CBAJ_G0026539
 protein coding gene Chr2:180935488-180938028 (-)
DBA/2J MGP_DBA2J_G0026677
 protein coding gene Chr2:161970386-161972892 (-)
FVB/NJ MGP_FVBNJ_G0026643
 protein coding gene Chr2:160377152-160379940 (-)
LP/J MGP_LPJ_G0026780
 protein coding gene Chr2:169775672-169778077 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026663
 protein coding gene Chr2:184553373-184555793 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027322
 protein coding gene Chr2:167531482-167534468 (-)
PWK/PhJ MGP_PWKPhJ_G0025757
 protein coding gene Chr2:161551488-161553993 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025558
 protein coding gene Chr2:166393539-166396268 (-)
WSB/EiJ MGP_WSBEiJ_G0026092
 protein coding gene Chr2:168390475-168393406 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
This locus controls multi-band electrophoretic variation in a secreted seminal vesicle protein. Three alleles are known: the a allele occurs in C57BL/6; the b allele in AKR and CBA; the c allele in C3H/He, DBA/2 and BALB/c. Heterozygotes have patterns resembling mixtures of the parental types.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20941 NCBI Gene Model | MGI Sequence Detail 2352 C57BL/6J ±  kb
transcript NM_009300 RefSeq | MGI Sequence Detail 575 ZRU/MplStud  
polypeptide P18419 UniProt | EBI | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-14660, MGD-MRK-14662, MGD-MRK-14664, MGD-MRK-14666, MGI:98452
References
more
  • Summaries
    All 36
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:15025 Moutier R, et al., Controle genetique des proteines de la secretion des glandes seminales chez la souris et le rat. Exp Animale. 1971;4:7-18
  • Latest
    J:291572 Shindo M, et al., Deletion of a Seminal Gene Cluster Reinforces a Crucial Role of SVS2 in Male Fertility. Int J Mol Sci. 2019 Sep 14;20(18):4557
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory