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Sox14 Gene Detail
Summary
  • Symbol
    Sox14
  • Name
    SRY (sex determining region Y)-box 14
  • Feature Type
    protein coding gene
  • IDs
    MGI:98362
    NCBI Gene: 20669
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:99756159-99758223 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 52.11 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98362
 protein coding gene Chr9:99756159-99758223 (-)
129S1/SvImJ ENSMUSG00200015607
 protein coding gene Chr9:96876815-96878879 (-)
A/J ENSMUSG00195016781
 protein coding gene Chr9:96115303-96117375 (-)
AKR/J ENSMUSG00220033926
 protein coding gene Chr9:96478482-96480547 (-)
BALB/cJ ENSMUSG00180023684
 protein coding gene Chr9:96434900-96436972 (-)
C3H/HeJ ENSMUSG00175012498
 protein coding gene Chr9:96777673-96779745 (-)
C57BL/6NJ ENSMUSG00215015687
 protein coding gene Chr9:96774350-96776414 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032568
 protein coding gene Chr9:95394886-95396945 (-)
CAST/EiJ ENSTCUG00005013031
 protein coding gene Chr9:96592138-96594198 (-)
CBA/J ENSMUSG00210014739
 protein coding gene Chr9:96610756-96612828 (-)
DBA/2J ENSMUSG00185010835
 protein coding gene Chr9:96779287-96781371 (-)
FVB/NJ ENSMUSG00205021106
 protein coding gene Chr9:96774210-96776274 (-)
JF1/MsJ ENSUMUG00000029531
 protein coding gene Chr9:96583007-96585072 (-)
LP/J ENSMUSG00230015495
 protein coding gene Chr9:96953254-96955318 (-)
NOD/ShiLtJ ENSMUSG00190036064
 protein coding gene Chr9:96417263-96419341 (-)
NZO/HlLtJ ENSMUSG00225018895
 protein coding gene Chr9:97146141-97148206 (-)
PWK/PhJ ENSLUMG00010023566
 protein coding gene Chr9:96548249-96550314 (-)
SPRET/EiJ ENSMSPG00010003527
 protein coding gene Chr9:98372947-98374999 (-)
WSB/EiJ ENSIUOG00005024063
 protein coding gene Chr9:95857407-95859479 (-)



Homology
more
  • Human Ortholog
    SOX14, SRY-box transcription factor 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SOX14, SRY-box transcription factor 14
  • Synonyms
    SOX28
  • Links
    NCBI Gene ID: 8403
    UniProt: O95416

  • Chr Location
    3q22.3; chr3:137764315-137766334 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    776
  • Tissues
    148
  • cDNA Data
    7
  • Literature Summary
    50
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 20669 NCBI Gene Model | MGI Sequence Detail 2065 C57BL/6J ±  kb
    transcript NM_011440 RefSeq | MGI Sequence Detail 2075 ZRU/MplStud  
    polypeptide Q04892 UniProt | EBI | MGI Sequence Detail 240 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      Genomic 3
      cDNA 8
      Primer pair 2
      Other 6

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-14501
    References
    more
    • Summaries
      All 92
      Developmental Gene Expression 50
      Gene Ontology 9
      Phenotypes 19
    • Earliest
      J:4011 Wright EM, et al., Seven new members of the Sox gene family expressed during mouse development. Nucleic Acids Res. 1993 Feb 11;21(3):744
    • Latest
      J:370996 Khouri-Farah N, et al., FOXP genes regulate Purkinje cell diversity and cerebellar morphogenesis. Nat Neurosci. 2025 Aug 18;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory