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Rps14 Gene Detail
Summary
  • Symbol
    Rps14
  • Name
    ribosomal protein S14
  • Synonyms
    2600014J02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:98107
    NCBI Gene: 20044
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:60907668-60911618 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 34.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98107
 protein coding gene Chr18:60880170-60911618 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024467
 protein coding gene Chr18:60604588-60608624 (+)
A/J MGP_AJ_G0024434
 protein coding gene Chr18:58008139-58012264 (+)
AKR/J MGP_AKRJ_G0024404
 protein coding gene Chr18:59605276-59609314 (+)
BALB/cJ MGP_BALBcJ_G0024433
 protein coding gene Chr18:58137286-58141435 (+)
C3H/HeJ MGP_C3HHeJ_G0024201
 protein coding gene Chr18:59840782-59844818 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024880
 protein coding gene Chr18:62257222-62261258 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022311
 protein coding gene Chr18:57559131-57563229 (+)
CAST/EiJ MGP_CASTEiJ_G0023674
 protein coding gene Chr18:59705601-59710583 (+)
CBA/J MGP_CBAJ_G0024171
 protein coding gene Chr18:64274541-64278686 (+)
DBA/2J MGP_DBA2J_G0024301
 protein coding gene Chr18:57687749-57691785 (+)
FVB/NJ MGP_FVBNJ_G0024267
 protein coding gene Chr18:57093730-57097771 (+)
LP/J MGP_LPJ_G0024384
 protein coding gene Chr18:60461569-60465605 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024296
 protein coding gene Chr18:65910968-65915021 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024927
 protein coding gene Chr18:59805168-59809204 (+)
PWK/PhJ MGP_PWKPhJ_G0023417
 protein coding gene Chr18:57912315-57916459 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023223
 protein coding gene Chr18:60042767-60046922 (+)
WSB/EiJ MGP_WSBEiJ_G0023738
 protein coding gene Chr18:59656761-59660797 (+)



Homology
more
  • Human Ortholog
    RPS14, ribosomal protein S14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPS14, ribosomal protein S14
  • Synonyms
    EMTB, S14, uS11
  • Links
    NCBI Gene ID: 6208
    neXtProt AC: NX_P62263
    UniProt: P62263

  • Chr Location
    5q33.1; chr5:150442635-150449739 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RPS14 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Conditional heterozygous knockout in hematopoietic cells leads to reduced protein synthesis, resulting in progressive anemia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    4
  • cDNA Data
    674
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 20044 NCBI Gene Model | MGI Sequence Detail 3951 C57BL/6J ±  kb
    transcript NM_020600 RefSeq | MGI Sequence Detail 606 ZRU/MplStud  
    polypeptide P62264 UniProt | EBI | MGI Sequence Detail 151 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 676
      cDNA 675
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-14133, MGI:1914326, MGI:2139854
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 6
      Gene Ontology 11
      Phenotypes 11
    • Earliest
      J:1700 Johnson KR, et al., A multipoint genetic linkage map of mouse chromosome 18. Genomics. 1992 Aug;13(4):1143-9
    • Latest
      J:344838 Sharma S, et al., Uncovering a mammalian neural-specific poly(A) binding protein with unique properties. Genes Dev. 2023 Aug 1;37(15-16):760-777
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory