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Nfyb Gene Detail
Summary
  • Symbol
    Nfyb
  • Name
    nuclear transcription factor-Y beta
  • Synonyms
    Cbf-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:97317
    NCBI Gene: 18045
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:82584535-82599978 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 40.25 cM, cytoband C3-D1
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97317
 protein coding gene Chr10:82584534-82599985 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017580
 protein coding gene Chr10:83489863-83505311 (-)
A/J MGP_AJ_G0017560
 protein coding gene Chr10:80684387-80699838 (-)
AKR/J MGP_AKRJ_G0017519
 protein coding gene Chr10:82932123-82947573 (-)
BALB/cJ MGP_BALBcJ_G0017523
 protein coding gene Chr10:80953331-80968782 (-)
C3H/HeJ MGP_C3HHeJ_G0017345
 protein coding gene Chr10:83003614-83019062 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017980
 protein coding gene Chr10:86421968-86437409 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015665
 protein coding gene Chr10:76424174-76439885 (-)
CAST/EiJ MGP_CASTEiJ_G0016912
 protein coding gene Chr10:82912473-82927891 (-)
CBA/J MGP_CBAJ_G0017315
 protein coding gene Chr10:89981420-89996871 (-)
DBA/2J MGP_DBA2J_G0017421
 protein coding gene Chr10:79859331-79874776 (-)
FVB/NJ MGP_FVBNJ_G0017415
 protein coding gene Chr10:79089793-79105281 (-)
LP/J MGP_LPJ_G0017493
 protein coding gene Chr10:84146561-84162014 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017443
 protein coding gene Chr10:91662183-91677673 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018017
 protein coding gene Chr10:82862381-82877846 (-)
PWK/PhJ MGP_PWKPhJ_G0016693
 protein coding gene Chr10:79738150-79753601 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016483
 protein coding gene Chr10:81558273-81573714 (-)
WSB/EiJ MGP_WSBEiJ_G0016971
 protein coding gene Chr10:82897357-82914372 (-)



Homology
more
  • Human Ortholog
    NFYB, nuclear transcription factor Y subunit beta
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NFYB, nuclear transcription factor Y subunit beta
  • Synonyms
    CBF-A, CBF-B, HAP3, NF-YB
  • Links
    NCBI Gene ID: 4801
    neXtProt AC: NX_P25208
    UniProt: P25208

  • Chr Location
    12q23.3; chr12:104117086-104138241 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    880
  • Tissues
    167
  • cDNA Data
    80
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020248 Ensembl Gene Model | MGI Sequence Detail 15444 C57BL/6J ±  kb
transcript ENSMUST00000130911 Ensembl | MGI Sequence Detail 2554 Not Applicable  
polypeptide ENSMUSP00000122403 Ensembl | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 85
    Genomic 1
    cDNA 80
    Primer pair 4

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-12836, MGI:2143515
References
more
  • Summaries
    All 73
    Developmental Gene Expression 11
    Gene Ontology 13
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:229124 Guess MG, et al., miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. PLoS One. 2015;10(2):e0118229
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory