About   Help   FAQ
Mcpt2 Gene Detail
Summary
  • Symbol
    Mcpt2
  • Name
    mast cell protease 2
  • Synonyms
    Mcp-2, MMCP-2, MMCP-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:96938
    NCBI Gene: 17225
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr14:56279498-56282099 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    87 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96938
 protein coding gene Chr14:56259041-56282099 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021380
 protein coding gene Chr14:50118836-50121347 (+)
A/J MGP_AJ_G0021339
 protein coding gene Chr14:49118554-49121065 (+)
AKR/J MGP_AKRJ_G0021315
 protein coding gene Chr14:50883701-50886212 (+)
BALB/cJ MGP_BALBcJ_G0021343
 protein coding gene Chr14:49092208-49094719 (+)
C3H/HeJ MGP_C3HHeJ_G0021123
 protein coding gene Chr14:50565265-50567776 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021782
 protein coding gene Chr14:52629211-52631722 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0020642
 protein coding gene Chr14:46840898-46843409 (+)
CBA/J MGP_CBAJ_G0021090
 protein coding gene Chr14:54189594-54192105 (+)
DBA/2J MGP_DBA2J_G0021211
 protein coding gene Chr14:48848950-48851461 (+)
FVB/NJ MGP_FVBNJ_G0021193
 protein coding gene Chr14:48268876-48271387 (+)
LP/J MGP_LPJ_G0021285
 protein coding gene Chr14:51165031-51167542 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021217
 protein coding gene Chr14:53538903-53541414 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021809
 protein coding gene Chr14:50072343-50074854 (+)
PWK/PhJ MGP_PWKPhJ_G0020387
 protein coding gene Chr14:45369266-45371725 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020216
 protein coding gene Chr14:46061774-46064278 (+)
WSB/EiJ MGP_WSBEiJ_G0020695
 protein coding gene Chr14:50330666-50333177 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    52
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022226 Ensembl Gene Model | MGI Sequence Detail 2602 C57BL/6J ±  kb
transcript ENSMUST00000015576 Ensembl | MGI Sequence Detail 1061 Not Applicable  
polypeptide ENSMUSP00000015576 Ensembl | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    Genomic 5
    cDNA 52

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-12144, MGD-MRK-12152
References
more
  • Summaries
    All 38
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:10169 Serafin WE, et al., Identification and molecular cloning of a novel mouse mucosal mast cell serine protease. J Biol Chem. 1990 Jan 5;265(1):423-9
  • Latest
    J:287176 Kasakura K, et al., Cooperative Regulation of the Mucosal Mast Cell-Specific Protease Genes Mcpt1 and Mcpt2 by GATA and Smad Transcription Factors. J Immunol. 2020 Mar 15;204(6):1641-1649
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory