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Tmem165 Gene Detail
Summary
  • Symbol
    Tmem165
  • Name
    transmembrane protein 165
  • Synonyms
    pFT27, Tpardl, Tparl
  • Feature Type
    protein coding gene
  • IDs
    MGI:894407
    NCBI Gene: 21982
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:76331727-76357091 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 40.56 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    187 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_894407
 protein coding gene Chr5:76331727-76357092 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029641
 protein coding gene Chr5:76360485-76385135 (+)
A/J MGP_AJ_G0029609
 protein coding gene Chr5:73436243-73464142 (+)
AKR/J MGP_AKRJ_G0029557
 protein coding gene Chr5:75823056-75852737 (+)
BALB/cJ MGP_BALBcJ_G0029618
 protein coding gene Chr5:74181107-74205696 (+)
C3H/HeJ MGP_C3HHeJ_G0029341
 protein coding gene Chr5:76211470-76239030 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030072
 protein coding gene Chr5:79421868-79451093 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027313
 protein coding gene Chr5:69096227-69124539 (+)
CAST/EiJ MGP_CASTEiJ_G0028749
 protein coding gene Chr5:75394177-75420186 (+)
CBA/J MGP_CBAJ_G0029310
 protein coding gene Chr5:82009232-82033798 (+)
DBA/2J MGP_DBA2J_G0029455
 protein coding gene Chr5:73513275-73545147 (+)
FVB/NJ MGP_FVBNJ_G0029416
 protein coding gene Chr5:72691546-72719822 (+)
LP/J MGP_LPJ_G0029542
 protein coding gene Chr5:76801219-76825931 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029444
 protein coding gene Chr5:85191079-85219568 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030105
 protein coding gene Chr5:75391047-75416638 (+)
PWK/PhJ MGP_PWKPhJ_G0028472
 protein coding gene Chr5:72519739-72549042 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028307
 protein coding gene Chr5:74750760-74782119 (+)
WSB/EiJ MGP_WSBEiJ_G0028829
 protein coding gene Chr5:75695720-75724444 (+)



Homology
more
  • Human Ortholog
    TMEM165, transmembrane protein 165
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM165, transmembrane protein 165
  • Synonyms
    CDG2K, FT27, GDT1, SLC64A1, TMPT27, TPARL
  • Links
    NCBI Gene ID: 55858
    neXtProt AC: NX_Q9HC07
    UniProt: Q9HC07

  • Chr Location
    4q12; chr4:55395957-55453397 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TMEM165 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    123
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21982 NCBI Gene Model | MGI Sequence Detail 25365 C57BL/6J ±  kb
    transcript NM_011626 RefSeq | MGI Sequence Detail 1896 C57BL/6  
    polypeptide P52875 UniProt | EBI | MGI Sequence Detail 323 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 127
      Genomic 4
      cDNA 123

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2141106
    References
    more
    • Summaries
      All 45
      Gene Ontology 6
      Phenotypes 15
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory