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Cd9 Gene Detail
Summary
  • Symbol
    Cd9
  • Name
    CD9 antigen
  • Synonyms
    Tspan29
  • Feature Type
    protein coding gene
  • IDs
    MGI:88348
    NCBI Gene: 12527
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:125437229-125471723 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.32 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88348
 protein coding gene Chr6:125437229-125471754 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031298
 protein coding gene Chr6:128819271-128858913 (-)
A/J MGP_AJ_G0031269
 protein coding gene Chr6:123947798-123984125 (-)
AKR/J MGP_AKRJ_G0031197
 protein coding gene Chr6:127338279-127374519 (-)
BALB/cJ MGP_BALBcJ_G0031276
 protein coding gene Chr6:123535099-123571383 (-)
C3H/HeJ MGP_C3HHeJ_G0031000
 protein coding gene Chr6:127409952-127447748 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031733
 protein coding gene Chr6:132218792-132258399 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028881
 protein coding gene Chr6:121162868-121195418 (-)
CAST/EiJ MGP_CASTEiJ_G0030381
 protein coding gene Chr6:127615002-127653055 (-)
CBA/J MGP_CBAJ_G0030961
 protein coding gene Chr6:137273106-137318033 (-)
DBA/2J MGP_DBA2J_G0031117
 protein coding gene Chr6:122869275-122905061 (-)
FVB/NJ MGP_FVBNJ_G0031066
 protein coding gene Chr6:121784485-121822096 (-)
LP/J MGP_LPJ_G0031197
 protein coding gene Chr6:128970265-129005746 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031105
 protein coding gene Chr6:141298546-141337686 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031768
 protein coding gene Chr6:127244192-127283434 (-)
PWK/PhJ MGP_PWKPhJ_G0030096
 protein coding gene Chr6:121115707-121151781 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029925
 protein coding gene Chr6:125309862-125349538 (-)
WSB/EiJ MGP_WSBEiJ_G0030466
 protein coding gene Chr6:127609116-127646683 (-)



Homology
more
  • Human Ortholog
    CD9, CD9 molecule
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD9, CD9 molecule
  • Synonyms
    BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN29, TSPAN-29
  • Links
    NCBI Gene ID: 928
    neXtProt AC: NX_P21926
    UniProt: P21926

  • Chr Location
    12p13.31; chr12:6199715-6238271 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CD9 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 3 alleles in 3 genetic backgrounds
    11 phenotypes from multigenic genotypes
    57 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Females homozygous for targeted null mutations are infertile due to lack of sperm-egg fusion. Mice heterozygous for conditional alleles activated in pancreatic cells exhibit reduced tumor growth in a pancreatic tumor mouse model.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    20
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    936
  • Tissues
    60
  • cDNA Data
    12
  • Literature Summary
    23
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12527 NCBI Gene Model | MGI Sequence Detail 34495 C57BL/6J ±  kb
    transcript NM_007657 RefSeq | MGI Sequence Detail 1227 ZRU/MplStud  
    polypeptide P40240 UniProt | EBI | MGI Sequence Detail 226 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 12
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-1874
    References
    more
    • Summaries
      All 134
      Developmental Gene Expression 23
      Gene Ontology 20
      Phenotypes 57
    • Earliest
      J:15493 Rubinstein E, et al., Molecular cloning of the mouse equivalent of CD9 antigen. Thromb Res. 1993 Sep 1;71(5):377-83
    • Latest
      J:345878 Fukuoka A, et al., Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring. Development. 2024 Feb 15;151(4)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory