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Gene Expression Data
Assay Details
Assay
Reference: J:337458 Waldhauser V, et al., PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7865665
Gene symbol: Pbrm1
Gene name: polybromo 1
Antibody: anti-Pbrm1
Results
Specimen 1A E16.5 Pbrm1: embryonic day 16.5 (more )
Note: Double labeled: red - Pbrm1; green - Sox10 (assay MGI:7865666).
Structure Cell Type Level Pattern Image Note
TS24: spinal cord oligodendrocyte precursor cell Present 1A E16.5 Pbrm1 , 1A E16.5 merged Expression in oligodendroglial cells from E16.5 when most are still in the oligodendrocyte precursor cell stage.
Specimen 1A P0 Pbrm1: postnatal day 0 (more )
Note: Double labeled: red - Pbrm1; green - Sox10 (assay MGI:7865666).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord oligodendrocyte Present 1A P0 merged , 1A P0 Pbrm1 Expression in oligodendroglial cells to P21.
Specimen 1A P7 Pbrm1: postnatal day 7 (more )
Note: Double labeled: red - Pbrm1; green - Sox10 (assay MGI:7865666).
Structure Cell Type Level Pattern Image Note
TS28: spinal cord spinal cord oligodendrocyte Present 1A P7 Pbrm1 , 1A P7 merged Expression in oligodendroglial cells to P21.
Specimen 1A P14 Pbrm1: postnatal day 14 (more )
Note: Double labeled: red - Pbrm1; green - Sox10 (assay MGI:7865666).
Structure Cell Type Level Pattern Image Note
TS28: spinal cord spinal cord oligodendrocyte Present 1A P14 merged , 1A P14 Pbrm1 Expression in oligodendroglial cells to P21.
Specimen 1A P21 Pbrm1: postnatal day 21 (more )
Note: Double labeled: red - Pbrm1; green - Sox10 (assay MGI:7865666).
Structure Cell Type Level Pattern Image Note
TS28: spinal cord spinal cord oligodendrocyte Present 1A P21 Pbrm1 , 1A P21 merged Expression in oligodendroglial cells to P21.
Specimen 1B Pbrm1: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: spinal cord astrocyte of the spinal cord Present 1B Pbrm1 Expression in oligodendroglial cells, astrocytes and neurons.
TS27: spinal cord neuron Present 1B Pbrm1 Expression in oligodendroglial cells, astrocytes and neurons.
TS27: spinal cord spinal cord oligodendrocyte Present 1B Pbrm1 Expression in oligodendroglial cells, astrocytes and neurons.
Specimen 1D Pbrm1 (Pdgfra): postnatal day 0 (more )
Note: Double labeled: red - Pbrm1; green - Pdgfra (assay MGI:7865671).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord oligodendrocyte precursor cell Present 1D Pdgfra Expression co-localized with Pdgfra in oligodendrocyte progenitor cells.
Specimen 1D Pbrm1 (Bcas1): postnatal day 0 (more )
Note: Double labeled: red - Pbrm1; green - Bcas1 (assay MGI:7865673).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord oligodendrocyte Present 1D Bcas1 Expression co-localized with Bcas1 in pre-myelinating oligodendroglial cells.
Specimen 1D Pbrm1 (Myrf): postnatal day 0 (more )
Note: Double labeled: red - Pbrm1; green - Myrf (assay MGI:7865680).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord oligodendrocyte Present 1D Myrf Expression co-localized with Myrf in myelinating oligodendroglial cells.
Specimen 1D Pbrm1 (Mbp): postnatal day 0 (more )
Note: Double labeled: red - Pbrm1; green - Mbp (assay MGI:7865681).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord oligodendrocyte Present 1D Mbp Expression co-localized with Mbp in mature myelinating oligodendroglial cells.
Specimen 2A Ctrl Pbrm1: postnatal day 0 (more )
Note: Double labeled: red - Pbrm1; green - Sox10 (assay MGI:7865666).
Structure Level Pattern Image Note
TS27: spinal cord Present 2A Ctrl Pbrm1 , 2A Ctrl merged
Specimen 2A deltaCnp Pbrm1: postnatal day 0; Cnptm1(cre)Kan/Cnp+, Pbrm1tm1Zhwa/Pbrm1tm1Zhwa (more )
Note: Conditional mutant. Double labeled: red - Pbrm1; green - Sox10 (assay MGI:7865666).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord oligodendrocyte Trace 2A deltaCnp Pbrm1 , 2A deltaCnp merged Expression deleted in vast majority of oligodendroglial cells by P0.
TS27: spinal cord astrocyte of the spinal cord Present 2A deltaCnp Pbrm1 , 2A deltaCnp merged Expression in astrocytes and neurons.
TS27: spinal cord neuron Present 2A deltaCnp Pbrm1 , 2A deltaCnp merged Expression in astrocytes and neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory