About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:337458 Waldhauser V, et al., PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7865671
Gene symbol: Pdgfra
Gene name: platelet derived growth factor receptor, alpha polypeptide
Antibody: anti-Pdgfra (E-1210)
Assay notes: Two Pdgfra antibodies were described, but the one used in this assay was not detailed. Anti-Pdgfra (AF1062) MGI:6196519 may have been used in this assay.
Results
Specimen 1D Pdgfra: postnatal day 0 (more )
Note: Double labeled: green - Pdgfra; red - Pbrm1 (assay MGI:7865665).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord oligodendrocyte precursor cell Present 1D Pdgfra Expression in oligodendrocyte progenitor cells.
Specimen deltaCnp P0 Olig2 not shown: postnatal day 0; Cnptm1(cre)Kan/Cnp+, Pbrm1tm1Zhwa/Pbrm1tm1Zhwa (more )
Note: Conditional mutant. Data shown in Figure 2F.
Structure Level Pattern Image Note
TS27: spinal cord Present Total number of expressing cells comparable to control.
Specimen Ctrl P7 Olig2 not shown: postnatal day 7 (more )
Note: Data shown in Figure 2F.
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte precursor cell Present Expression in oligodendrocyte progenitor cells.
Specimen deltaCnp P7 Olig2 not shown: postnatal day 7; Cnptm1(cre)Kan/Cnp+, Pbrm1tm1Zhwa/Pbrm1tm1Zhwa (more )
Note: Conditional mutant. Data shown in Figure 2F.
Structure Level Pattern Image Note
TS28: spinal cord Present Total number of expressing cells comparable to control.
Specimen 4H E16.5 Ctrl: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: spinal cord oligodendrocyte precursor cell Present 4H Ctrl E16.5 Expression in oligodendrocyte progenitor cells.
Specimen 4H E16.5 deltaSox10: embryonic day 16.5; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: spinal cord Present 4H deltaSox10 E16.5 pNumber of expressing cells similar to control at all times analyzed.
Specimen 4H P0 Ctrl: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: spinal cord oligodendrocyte precursor cell Present 4H Ctrl P0 Expression in oligodendrocyte progenitor cells.
Specimen 4H P0 deltaSox10: postnatal day 0; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Present 4H deltaSox10 P0 Number of expressing cells similar to control at all times analyzed.
Specimen 4H P7 Ctrl: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte precursor cell Present 4H Ctrl P7 Expression in oligodendrocyte progenitor cells.
Specimen 4H P7 deltaSox10: postnatal day 7; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 4H deltaSox10 P7 Number of expressing cells similar to control at all times analyzed.
Specimen 4H P14 Ctrl: postnatal day 14 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte precursor cell Present 4H Ctrl P14 Expression in oligodendrocyte progenitor cells.
Specimen 4H P14 deltaSox10: postnatal day 14; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 4H deltaSox10 P14 Number of expressing cells similar to control at all times analyzed.
Specimen 4H P21 Ctrl: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte precursor cell Present 4H Ctrl P21 Expression in oligodendrocyte progenitor cells.
Specimen 4H P21 deltaSox10: postnatal day 21; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 4H deltaSox10 P21 Number of expressing cells similar to control at all times analyzed.
Specimen P7 Ctrl not shown: postnatal day 7 (more )
Note: Data shown in Figure 8C.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte precursor cell Present Expression in oligodendrocyte progenitor cells.
Specimen P7 deltaSox10 not shown: postnatal day 7; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant. Data shown in Figure 8C.
Structure Level Pattern Image Note
TS28: corpus callosum Present No difference in expressing cells compared to control at P7 or P21.
Specimen P21 Ctrl not shown: postnatal day 21 (more )
Note: Data shown in Figure 8C.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte precursor cell Present Expression in oligodendrocyte progenitor cells.
Specimen P21 deltaSox10 not shown: postnatal day 21; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant. Data shown in Figure 8C.
Structure Level Pattern Image Note
TS28: corpus callosum Present No difference in expressing cells compared to control at P7 or P21.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/06/2026
MGI 6.29 		The Jackson Laboratory